PDB ID:  pdb_00002v0m
  • Crystal structure of human P450 3A4 in complex with ketoconazole
  • Experimental method: X-RAY DIFFRACTION
  • Resolution: 2.8 Å
  • Deposition date: 2007-05-15
Number of assemblies:  4
Assembly ID:  1  (author_and_software_defined_assembly)    
Structural data modeled
Oligomeric count 1
label_asym_ids of protein
label_asym_ids of heme
label_asym_ids of the others F (KLNStructure of KLNKLN ), G (KLNStructure of KLNKLN )
Each chain information
Chain A heme  
auth_asym_id A
Residue indices (Uniprot) 30-498 (25-503)
Missing residues 264THR-268ARG:280ASN-288LYS
Structural gaps Exists
Uniprot ID P08684 →UniprotKB
label_asym_ids of heme E
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.11 Å
Assembly ID:  2  (author_and_software_defined_assembly)    
Structural data modeled
Oligomeric count 1
label_asym_ids of protein
label_asym_ids of heme
label_asym_ids of the others I (KLNStructure of KLNKLN ), J (KLNStructure of KLNKLN )
Each chain information
Chain B heme  
auth_asym_id B
Residue indices (Uniprot) 30-496 (25-503)
Missing residues 214ASP-215PHE:264THR-268ARG:280ASN-288LYS
Structural gaps Exists
Uniprot ID P08684 →UniprotKB
label_asym_ids of heme H
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.12 Å
Assembly ID:  3  (author_and_software_defined_assembly)    
Structural data modeled
Oligomeric count 1
label_asym_ids of protein
label_asym_ids of heme
label_asym_ids of the others L (KLNStructure of KLNKLN ), M (KLNStructure of KLNKLN )
Each chain information
Chain C heme  
auth_asym_id C
Residue indices (Uniprot) 30-496 (25-503)
Missing residues 212ARG-213PHE
Structural gaps Exists
Uniprot ID P08684 →UniprotKB
label_asym_ids of heme K
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.11 Å
Assembly ID:  4  (author_and_software_defined_assembly)    
Structural data modeled
Oligomeric count 1
label_asym_ids of protein
label_asym_ids of heme
label_asym_ids of the others O (KLNStructure of KLNKLN ), P (KLNStructure of KLNKLN )
Each chain information
Chain D heme  
auth_asym_id D
Residue indices (Uniprot) 30-496 (25-503)
Missing residues 264THR-268ARG:280ASN-288LYS
Structural gaps Exists
Uniprot ID P08684 →UniprotKB
label_asym_ids of heme N
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.11 Å