PDB ID:  pdb_00004otj
  • The complex of murine cyclooxygenase-2 with a conjugate of indomefathin and podophyllotoxin, N-{(succinylpodophyllotoxinyl)but-4-yl}-2-{1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl}acetamide
  • Experimental method: X-RAY DIFFRACTION
  • Resolution: 2.11 Å
  • Deposition date: 2014-02-13
Number of assemblies:  2
Assembly ID:  1  (author_and_software_defined_assembly)    
Structural data PDB
Oligomeric count 2
label_asym_ids of protein
label_asym_ids of heme
label_asym_ids of the others E (NAGStructure of NAGNAG ), F (NAGStructure of NAGNAG ), I (NAGStructure of NAGNAG ), J (NAGStructure of NAGNAG ), L (IXPStructure of IXPIXP ), M (BOGStructure of BOGBOG ), N (NAGStructure of NAGNAG ), O (NAGStructure of NAGNAG ), Q (IXPStructure of IXPIXP )
Each chain information
Chain A heme  
auth_asym_id A
Residue indices (Uniprot) 33-583 (18-604)
Uniprot ID Q05769 →UniprotKB
S-S bonds 36:47,37:159,41:57,59:69,569:575
label_asym_ids of heme K
Available structure PDB
Chain B heme  
auth_asym_id B
Residue indices (Uniprot) 33-582 (18-604)
Uniprot ID Q05769 →UniprotKB
S-S bonds 36:47,37:159,41:57,59:69,569:575
label_asym_ids of heme P
Available structure PDB
Assembly ID:  2  (author_and_software_defined_assembly)    
Structural data PDB
Oligomeric count 2
label_asym_ids of protein
label_asym_ids of heme
label_asym_ids of the others G (NAGStructure of NAGNAG ), H (NAGStructure of NAGNAG ), R (NAGStructure of NAGNAG ), S (NAGStructure of NAGNAG ), U (IXPStructure of IXPIXP ), V (NAGStructure of NAGNAG ), W (NAGStructure of NAGNAG ), Y (BOGStructure of BOGBOG ), Z (IXPStructure of IXPIXP )
Each chain information
Chain C heme  
auth_asym_id C
Residue indices (Uniprot) 33-583 (18-604)
Uniprot ID Q05769 →UniprotKB
S-S bonds 36:47,37:159,41:57,59:69,569:575
label_asym_ids of heme T
Available structure PDB
Chain D heme  
auth_asym_id D
Residue indices (Uniprot) 33-582 (18-604)
Uniprot ID Q05769 →UniprotKB
S-S bonds 36:47,37:159,41:57,59:69,569:575
label_asym_ids of heme X
Available structure PDB