PDB ID: pdb_00004xrz
- Human Cytochrome P450 2D6 BACE1 Inhibitor 6 Complex
- Experimental method: X-RAY DIFFRACTION
- Resolution: 2.4 Å
- Deposition date: 2015-01-21
Number of assemblies: 4
| Structural data | modeled |
|---|---|
| Oligomeric count | 1 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
F (SI6  SI6
), G (ZN ZN
), H (ZNZN
), I (ZNZN
), J (GOL GOL
), K (ZNZN
), L (NA NA
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 31-497 (34-497) |
| Mutations (UniProt numbering) | |
| Missing residues | 40LEU-49VAL |
| Structural gaps | Exists |
| Uniprot ID | P10635 ￫UniprotKB |
| label_asym_ids of heme | E |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.11 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 1 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
N (SI6SI6
), O (ZNZN
), P (ZNZN
), Q (GOLGOL
), R (NANA
)
|
Each chain information
| auth_asym_id | B |
|---|---|
| Residue indices (Uniprot) | 31-497 (34-497) |
| Mutations (UniProt numbering) | |
| Missing residues | 40LEU-48HIS |
| Structural gaps | Exists |
| Uniprot ID | P10635 ￫UniprotKB |
| label_asym_ids of heme | M |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.11 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 1 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
T (SI6SI6
), U (ZNZN
), V (ZNZN
), W (ZNZN
), X (GOLGOL
), Y (NANA
)
|
Each chain information
| auth_asym_id | C |
|---|---|
| Residue indices (Uniprot) | 31-497 (34-497) |
| Mutations (UniProt numbering) | |
| Missing residues | 40LEU-51PHE |
| Structural gaps | Exists |
| Uniprot ID | P10635 ￫UniprotKB |
| label_asym_ids of heme | S |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.14 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 1 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
AA (SI6SI6
), BA (ZNZN
), CA (ZNZN
), DA (ZNZN
), EA (GOLGOL
), FA (NANA
)
|
Each chain information
| auth_asym_id | D |
|---|---|
| Residue indices (Uniprot) | 31-497 (34-497) |
| Mutations (UniProt numbering) | |
| Missing residues | 40LEU-51PHE |
| Structural gaps | Exists |
| Uniprot ID | P10635 ￫UniprotKB |
| label_asym_ids of heme | Z |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |