Danish
PDB ID:  pdb_00005gup
  • Cryo-EM structure of mammalian respiratory supercomplex I1III2IV1
  • Experimental method: ELECTRON MICROSCOPY
  • Resolution: unavailable
  • Deposition date: 2016-08-30
Number of assemblies:  1
Assembly ID:  0  (author_defined_assembly)    
Structural data including_not_modeled
Oligomeric count 80
label_asym_ids of protein
80 chains (5 with heme) A, AA, AB, AC, B, BA, BB, BC, C, CA, CB, D, DA, DB, E, EA, EB, F, FA, FB, G, GA, GB, H, HA, HB, I, IA, IB, J, JA, JB, K, KA, KB, L, LA, LB, M, MA, MB, N, NA, NB, O, OA, OB, P, PA, PB, Q, QA, QB, R, RA, RB, S, SA, SB, T, TA, TB, U, UA, UB, V, VA, VB, W, WA, WB, X, XA, XB, Y, YA, YB, Z, ZA, ZB
label_asym_ids of heme BD CD ED QD RD TD VD WD
label_asym_ids of the others
show AD (PEE), AE (CU), BE (ZN), CC (SF4), DC (FMN), DD (PEE), EC (FES), FC (SF4), FD (CDL), GC (SF4), GD (CDL), HC (FES), HD (PLX), IC (SF4), ID (PEE), JC (SF4), JD (FES), KC (PLX), KD (PLX), LC (SF4), LD (FES), MC (NDP), MD (CDL), NC (ZMP), ND (PEE), OC (CDL), OD (PEE), PC (PLX), PD (PEE), QC (PEE), RC (ZMP), SC (PEE), SD (CDL), TC (PLX), UC (CDL), UD (CDL), VC (PEE), WC (CDL), XC (PEE), XD (CU), YC (CDL), YD (MG), ZC (CDL), ZD (CU)
Each chain information

Showing all 80 chains (5 with heme). Show only chains with heme

Chain A  
auth_asym_id A
Residue indices (Uniprot) 1-73 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain AA  
auth_asym_id a
Residue indices (Uniprot) 52-189 (1-189)
Uniprot ID F1SGC6 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain AB  
auth_asym_id 0
Residue indices (Uniprot) 28-91 (1-91)
Uniprot ID F1S3W0 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain AC  
auth_asym_id Aq
Residue indices (Uniprot) 1-84 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain B  
auth_asym_id B
Residue indices (Uniprot) 47-456 (1-464)
Uniprot ID A0A4X1SZP7 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain BA  
auth_asym_id b
Residue indices (Uniprot) 3-126 (1-128)
Missing residues 38ARG-48ASN
Structural gaps Exists
Uniprot ID A0A4X1UIV8 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.31 Å
Chain BB  
auth_asym_id 1
Residue indices (Uniprot) 2-63 (1-64)
Uniprot ID Q2EN79 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain BC  
auth_asym_id Ar
Residue indices (Uniprot) 11-85 (-)
Uniprot ID Unavailable
S-S bonds 29:64
label_asym_ids of heme None
Available structure PDB
Chain C  
auth_asym_id C
Residue indices (Uniprot) 34-463 (7-469)
Uniprot ID F1S1A8 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain CA  
auth_asym_id c
Residue indices (Uniprot) 34-181 (1-186)
Uniprot ID F1RWL7 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain CB  
auth_asym_id 2
Residue indices (Uniprot) 79-274 (45-51)
Mutations (UniProt numbering) R12M, P15V, L16A, Y17S, A18R, P19S, A20G, L22F, E24P, G25V, R26L, P27S, G28A, D29T, P30S, P31R, F33V, Q34A, S35G, C36A, C37L, H39P, V40L, H56Q
Uniprot ID F1RNZ1 ￫UniprotKB
S-S bonds 222:238
label_asym_ids of heme None
Available structure PDB
Chain D  
auth_asym_id D
Residue indices (Uniprot) 43-250 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain DA  
auth_asym_id d
Residue indices (Uniprot) 4-172 (1-201)
Uniprot ID I3LDC3 ￫UniprotKB
S-S bonds 77:84,113:125
label_asym_ids of heme None
Available structure PDB
Chain DB  
auth_asym_id 3
Residue indices (Uniprot) 2-52 (1-56)
Uniprot ID F1SDI2 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain E  
auth_asym_id E
Residue indices (Uniprot) 11-219 (30-231)
Mutations (UniProt numbering) G1X, R2X, H3X, V4X, R5X, N6X, L7X, H8X, K9X, T10X, A11X, V12X, Q13X, N14X, G15X, A16X, G17X, G18X, A19X, L20X, F21X, V22X, H23X, R24X, D25X, T26X, P27X, E28X, N29X
Nonstandard amino acids UNK Structure of UNKUNK
Unknown residues Included
Uniprot ID F1SM98 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain EA  
auth_asym_id e
Residue indices (Uniprot) 54-150 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain EB  
auth_asym_id 4
Residue indices (Uniprot) 79-274 (52-55)
Mutations (UniProt numbering) R12M, P15V, L16A, Y17S, A18R, P19S, A20G, L22F, E24P, G25V, R26L, P27S, G28A, D29T, P30S, P31R, F33V, Q34A, S35G, C36A, C37L, H39P, V40L, H56Q
Uniprot ID F1RNZ1 ￫UniprotKB
S-S bonds 222:238
label_asym_ids of heme None
Available structure PDB
Chain F  
auth_asym_id F
Residue indices (Uniprot) 75-118 (1-123)
Uniprot ID F1S031 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain FA  
auth_asym_id f
Residue indices (Uniprot) 39-74 (1-7)
Mutations (UniProt numbering) T23A, V24A, G27L, G28L, Y29R, Y30P, T31F, Y32S, T34L, V35L, K36S, R37S, Q38A, A39R, K40L, H41P, E43G, H44S, T45S, N47R, M48S, E50F, K51Y, T52I, K53R, A54E, E55P, L56P, A72G, S74P, A76W, P77L, V78K, S80G, A82T, E83L, A84G, P85T, V86S, S183F, E184L, S185W, S186I, A187Y, G188L, G189I, D190K, L191Q, Q192H, E193K, A195D, G196V, G197L, A198E, S199Y, E200K, A201R, A202R, S203N, P204G, G206E
Uniprot ID F1RRC9 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain FB  
auth_asym_id 5
Residue indices (Uniprot) 35-480 (1-480)
Uniprot ID F1SKM0 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain G  
auth_asym_id G
Residue indices (Uniprot) 30-716 (1-727)
Missing residues 506VAL-519ILE
Structural gaps Exists
Uniprot ID A0A4X1V1H9 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.25 Å
Chain GA  
auth_asym_id g
Residue indices (Uniprot) 2-122 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain GB  
auth_asym_id 6
Residue indices (Uniprot) 35-452 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain H  
auth_asym_id H
Residue indices (Uniprot) 37-212 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain HA  
auth_asym_id h
Residue indices (Uniprot) 2-105 (1-106)
Uniprot ID F1SV23 ￫UniprotKB
S-S bonds 33:66,43:56
label_asym_ids of heme None
Available structure PDB
Chain HB heme  
auth_asym_id 7
Residue indices (Uniprot) 2-379 (1-379)
Uniprot ID Q1HBG9 ￫UniprotKB
label_asym_ids of heme QD ,  RD
Available structure PDB
Chain I  
auth_asym_id I
Residue indices (Uniprot) 61-216 (1-21)
Uniprot ID A0A8D1TL60 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain IA  
auth_asym_id i
Residue indices (Uniprot) 1-347 (1-347)
Uniprot ID O79875 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain IB heme  
auth_asym_id 8
Residue indices (Uniprot) 86-326 (-)
Uniprot ID Unavailable
label_asym_ids of heme TD
Available structure PDB
Chain J  
auth_asym_id J
Residue indices (Uniprot) 58-166 (1-175)
Uniprot ID G8IFA6 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain JA  
auth_asym_id j
Residue indices (Uniprot) 1-114 (1-115)
Uniprot ID O79880 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain JB  
auth_asym_id 9
Residue indices (Uniprot) 6-111 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain K  
auth_asym_id K
Residue indices (Uniprot) 1-97 (1-145)
Uniprot ID F1SQP4 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain KA  
auth_asym_id k
Residue indices (Uniprot) 1-97 (1-98)
Uniprot ID P56632 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain KB  
auth_asym_id Aa
Residue indices (Uniprot) 3-82 (1-82)
Uniprot ID A0A4X1UYT9 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain L  
auth_asym_id L
Residue indices (Uniprot) 40-376 (10-372)
Mutations (UniProt numbering) V2P, L3R, L4V, C5V, M6R, W7A, G8V, C9P, L10M, G12R
Uniprot ID F1SL07 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain LA  
auth_asym_id l
Residue indices (Uniprot) 1-606 (1-606)
Uniprot ID Q9TDR1 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain LB  
auth_asym_id Ab
Residue indices (Uniprot) 28-91 (1-91)
Uniprot ID F1S3W0 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain M  
auth_asym_id M
Residue indices (Uniprot) 4-113 (-)
Missing residues 75VAL-90THR
Structural gaps Exists
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.22 Å
Chain MA  
auth_asym_id m
Residue indices (Uniprot) 2-175 (1-175)
Uniprot ID O79882 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain MB  
auth_asym_id Ac
Residue indices (Uniprot) 2-63 (1-64)
Uniprot ID Q2EN79 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain N  
auth_asym_id N
Residue indices (Uniprot) 5-116 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain NA  
auth_asym_id n
Residue indices (Uniprot) 3-49 (1-58)
Uniprot ID A0A8D2CGH8 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain NB  
auth_asym_id Ad
Residue indices (Uniprot) 1-49 (1-56)
Uniprot ID F1SDI2 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain O  
auth_asym_id O
Residue indices (Uniprot) 72-156 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain OA  
auth_asym_id o
Residue indices (Uniprot) 2-129 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain OB  
auth_asym_id Ae
Residue indices (Uniprot) 1-57 (56-103)
Mutations (UniProt numbering) R12M, P15V, L16A, Y17S, A18R, P19S, A20G, L22F, E24P, G25V, R26L, P27S, G28A, D29T, P30S, P31R, F33V, Q34A, S35G, C36A, C37L, H39P, V40L, H56Q
Uniprot ID F1RNZ1 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain P  
auth_asym_id P
Residue indices (Uniprot) 14-96 (1-99)
Uniprot ID F1RGE3 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain PA  
auth_asym_id p
Residue indices (Uniprot) 4-179 (43-221)
Missing residues 161GLY-165PRO
Structural gaps Exists
Uniprot ID K7GSE5 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.21 Å
Chain PB  
auth_asym_id Af
Residue indices (Uniprot) 1-57 (56-103)
Mutations (UniProt numbering) R12M, P15V, L16A, Y17S, A18R, P19S, A20G, L22F, E24P, G25V, R26L, P27S, G28A, D29T, P30S, P31R, F33V, Q34A, S35G, C36A, C37L, H39P, V40L, H56Q
Uniprot ID F1RNZ1 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain Q  
auth_asym_id Q
Residue indices (Uniprot) 17-128 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain QA  
auth_asym_id q
Residue indices (Uniprot) 1-459 (1-459)
Uniprot ID O79881 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain QB  
auth_asym_id Ag
Residue indices (Uniprot) 1-43 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain R  
auth_asym_id R
Residue indices (Uniprot) 127-144 (1-145)
Uniprot ID F1SQP4 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain RA  
auth_asym_id r
Residue indices (Uniprot) 1-318 (1-318)
Uniprot ID O79874 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain RB  
auth_asym_id Ah
Residue indices (Uniprot) 1-56 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain S  
auth_asym_id S
Residue indices (Uniprot) 1-70 (1-70)
Mutations (UniProt numbering) C53R
Uniprot ID K7GR43 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain SA  
auth_asym_id s
Residue indices (Uniprot) 4-172 (78-249)
Uniprot ID F1SLR1 ￫UniprotKB
S-S bonds 46:56,78:110,88:100
label_asym_ids of heme None
Available structure PDB
Chain SB  
auth_asym_id Ai
Residue indices (Uniprot) 6-54 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain T  
auth_asym_id T
Residue indices (Uniprot) 3-84 (86-169)
Uniprot ID A0A4X1VPG4 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain TA  
auth_asym_id t
Residue indices (Uniprot) 3-124 (-)
Missing residues 14SER-20LEU
Structural gaps Exists
Uniprot ID Unavailable
S-S bonds 59:90,69:80
label_asym_ids of heme None
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.47 Å
Chain TB  
auth_asym_id Aj
Residue indices (Uniprot) 1-47 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain U  
auth_asym_id U
Residue indices (Uniprot) 47-357 (1-357)
Structural gaps Exists
Uniprot ID F1SIS9 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain UA  
auth_asym_id u
Residue indices (Uniprot) 35-480 (1-480)
Uniprot ID F1SKM0 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain UB heme  
auth_asym_id Ak
Residue indices (Uniprot) 1-514 (-)
Uniprot ID Unavailable
label_asym_ids of heme VD ,  WD
Available structure PDB
Chain V  
auth_asym_id V
Residue indices (Uniprot) 2-141 (1-141)
Uniprot ID I3LGM4 ￫UniprotKB
S-S bonds 95:115
label_asym_ids of heme None
Available structure PDB
Chain VA  
auth_asym_id v
Residue indices (Uniprot) 35-452 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain VB  
auth_asym_id Al
Residue indices (Uniprot) 1-227 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain W  
auth_asym_id W
Residue indices (Uniprot) 7-144 (1-144)
Uniprot ID A0A8D1NRT6 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain WA heme  
auth_asym_id w
Residue indices (Uniprot) 2-379 (1-379)
Uniprot ID Q1HBG9 ￫UniprotKB
label_asym_ids of heme BD ,  CD
Available structure PDB
Chain WB  
auth_asym_id Am
Residue indices (Uniprot) 1-261 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain X  
auth_asym_id X
Residue indices (Uniprot) 72-156 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain XA heme  
auth_asym_id x
Residue indices (Uniprot) 86-326 (-)
Uniprot ID Unavailable
label_asym_ids of heme ED
Available structure PDB
Chain XB  
auth_asym_id An
Residue indices (Uniprot) 4-147 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain Y  
auth_asym_id Y
Residue indices (Uniprot) 39-97 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain YA  
auth_asym_id y
Residue indices (Uniprot) 6-111 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB
Chain YB  
auth_asym_id Ao
Residue indices (Uniprot) 1-109 (44-152)
Uniprot ID F1SJ34 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain Z  
auth_asym_id Z
Residue indices (Uniprot) 12-89 (17-114)
Uniprot ID A0A4X1VBN1 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain ZA  
auth_asym_id z
Residue indices (Uniprot) 2-80 (1-82)
Uniprot ID A0A4X1UYT9 ￫UniprotKB
label_asym_ids of heme None
Available structure PDB
Chain ZB  
auth_asym_id Ap
Residue indices (Uniprot) 1-98 (-)
Uniprot ID Unavailable
label_asym_ids of heme None
Available structure PDB