PDB ID: pdb_00005whr
- Discovery of a novel and selective IDO-1 inhibitor PF-06840003 and its characterization as a potential clinical candidate.
- Experimental method: X-RAY DIFFRACTION
- Resolution: 2.28 Å
- Deposition date: 2017-07-18
Number of assemblies: 1
| Structural data | modeled |
|---|---|
| Oligomeric count | 2 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
D (AOJ  AOJ
), F (AOJAOJ
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 14-402 (12-403) |
| Mutations (UniProt numbering) | |
| Missing residues | 362PRO-375GLU |
| Structural gaps | Exists |
| Uniprot ID | P14902 ￫UniprotKB |
| label_asym_ids of heme | C |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.08 Å |
| auth_asym_id | B |
|---|---|
| Residue indices (Uniprot) | 12-401 (12-403) |
| Mutations (UniProt numbering) | |
| Missing residues | 361GLN-376ALA |
| Structural gaps | Exists |
| Uniprot ID | P14902 ￫UniprotKB |
| label_asym_ids of heme | E |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.10 Å |