PDB ID: pdb_00006csb
- V308E mutant of cytochrome P450 2D6 complexed with thioridazine
- Experimental method: X-RAY DIFFRACTION
- Resolution: 2.394 Å
- Deposition date: 2018-03-20
Number of assemblies: 4
| Structural data | modeled |
|---|---|
| Oligomeric count | 1 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
F (RTZ  RTZ
), G (RTZRTZ
), H (2CV 2CV
), I (ZN ZN
), J (ZNZN
), K (ZNZN
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 32-498 (34-497) |
| Mutations (UniProt numbering) | |
| Missing residues | 38LEU-52GLN |
| Structural gaps | Exists |
| Uniprot ID | P10635 ￫UniprotKB |
| label_asym_ids of heme | E |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.11 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 1 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
M (RTZRTZ
), N (RTZRTZ
), O (ACT ACT
), P (2CV2CV
), Q (ZNZN
), R (ZNZN
), S (ZNZN
)
|
Each chain information
| auth_asym_id | B |
|---|---|
| Residue indices (Uniprot) | 31-498 (34-497) |
| Mutations (UniProt numbering) | |
| Missing residues | 39PRO-51PHE |
| Structural gaps | Exists |
| Uniprot ID | P10635 ￫UniprotKB |
| label_asym_ids of heme | L |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.13 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 1 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
U (RTZRTZ
), V (RTZRTZ
), W (GOL GOL
), X (2CV2CV
), Y (ZNZN
), Z (ZNZN
)
|
Each chain information
| auth_asym_id | C |
|---|---|
| Residue indices (Uniprot) | 31-497 (34-497) |
| Mutations (UniProt numbering) | |
| Missing residues | 40LEU-52GLN |
| Structural gaps | Exists |
| Uniprot ID | P10635 ￫UniprotKB |
| label_asym_ids of heme | T |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.13 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 1 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
BA (RTZRTZ
), CA (RTZRTZ
), DA (ZNZN
)
|
Each chain information
| auth_asym_id | D |
|---|---|
| Residue indices (Uniprot) | 31-497 (34-497) |
| Mutations (UniProt numbering) | |
| Missing residues | 38LEU-51PHE |
| Structural gaps | Exists |
| Uniprot ID | P10635 ￫UniprotKB |
| label_asym_ids of heme | AA |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.13 Å |