PDB ID: pdb_00008fda
- Human Cytochrome P450 17A1 in complex with steroidal isonitrile inhibitor
- Experimental method: X-RAY DIFFRACTION
- Resolution: 2.2 Å
- Deposition date: 2022-12-02
Number of assemblies: 4
| Structural data | modeled |
|---|---|
| Oligomeric count | 2 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
F (XPK  XPK
), H (XPKXPK
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 28-503 (24-508) |
| Mutations (UniProt numbering) | |
| Missing residues | 274ASP-282GLN |
| Structural gaps | Exists |
| Uniprot ID | P05093 ￫UniprotKB |
| label_asym_ids of heme | E , E , E |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.13 Å |
| auth_asym_id | B |
|---|---|
| Residue indices (Uniprot) | 30-503 (24-508) |
| Mutations (UniProt numbering) | |
| Missing residues | 274ASP-282GLN |
| Structural gaps | Exists |
| Uniprot ID | P05093 ￫UniprotKB |
| label_asym_ids of heme | G , G |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.13 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 2 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
F (XPKXPK
), J (XPKXPK
), K (XPKXPK
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 28-503 (24-508) |
| Mutations (UniProt numbering) | |
| Missing residues | 274ASP-282GLN |
| Structural gaps | Exists |
| Uniprot ID | P05093 ￫UniprotKB |
| label_asym_ids of heme | E , E , E |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |
| auth_asym_id | C |
|---|---|
| Residue indices (Uniprot) | 30-504 (24-508) |
| Mutations (UniProt numbering) | |
| Missing residues | 275ASN-282GLN |
| Structural gaps | Exists |
| Uniprot ID | P05093 ￫UniprotKB |
| label_asym_ids of heme | I , I |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 3 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
F (XPKXPK
), J (XPKXPK
), K (XPKXPK
), M (XPKXPK
), N (XPKXPK
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 28-503 (24-508) |
| Mutations (UniProt numbering) | |
| Missing residues | 274ASP-282GLN |
| Structural gaps | Exists |
| Uniprot ID | P05093 ￫UniprotKB |
| label_asym_ids of heme | E , E , E |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.13 Å |
| auth_asym_id | C |
|---|---|
| Residue indices (Uniprot) | 30-504 (24-508) |
| Mutations (UniProt numbering) | |
| Missing residues | 275ASN-282GLN |
| Structural gaps | Exists |
| Uniprot ID | P05093 ￫UniprotKB |
| label_asym_ids of heme | I , I |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.10 Å |
| auth_asym_id | D |
|---|---|
| Residue indices (Uniprot) | 31-503 (24-508) |
| Mutations (UniProt numbering) | |
| Missing residues | 275ASN-281ASP |
| Structural gaps | Exists |
| Uniprot ID | P05093 ￫UniprotKB |
| label_asym_ids of heme | L , L |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 2 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
H (XPKXPK
), M (XPKXPK
), N (XPKXPK
)
|
Each chain information
| auth_asym_id | B |
|---|---|
| Residue indices (Uniprot) | 30-503 (24-508) |
| Mutations (UniProt numbering) | |
| Missing residues | 274ASP-282GLN |
| Structural gaps | Exists |
| Uniprot ID | P05093 ￫UniprotKB |
| label_asym_ids of heme | G , G |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |
| auth_asym_id | D |
|---|---|
| Residue indices (Uniprot) | 31-503 (24-508) |
| Mutations (UniProt numbering) | |
| Missing residues | 275ASN-281ASP |
| Structural gaps | Exists |
| Uniprot ID | P05093 ￫UniprotKB |
| label_asym_ids of heme | L , L |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |