PDB ID: pdb_00008fgj
- Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)-4-methoxypyridin-2-amine
- Experimental method: X-RAY DIFFRACTION
- Resolution: 2.15 Å
- Deposition date: 2022-12-12
Number of assemblies: 2
| Structural data | modeled |
|---|---|
| Oligomeric count | 2 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
F (H4B  H4B
), G (XVZ XVZ
), H (GOL GOL
), I (GOLGOL
), J (ZN ZN
), L (H4BH4B
), M (XVZXVZ
), N (XVZXVZ
), O (GOLGOL
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 304-722 (302-722) |
| Mutations (UniProt numbering) | |
| Missing residues | 344SER-353VAL |
| Structural gaps | Exists |
| Uniprot ID | P29475 ￫UniprotKB |
| label_asym_ids of heme | E |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.11 Å |
| auth_asym_id | B |
|---|---|
| Residue indices (Uniprot) | 304-722 (302-722) |
| Mutations (UniProt numbering) | |
| Missing residues | 345GLN-350PRO |
| Structural gaps | Exists |
| Uniprot ID | P29475 ￫UniprotKB |
| label_asym_ids of heme | K |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 2 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
Q (H4BH4B
), R (XVZXVZ
), S (XVZXVZ
), T (GOLGOL
), U (GOLGOL
), V (ZNZN
), X (H4BH4B
), Y (XVZXVZ
), Z (GOLGOL
)
|
Each chain information
| auth_asym_id | C |
|---|---|
| Residue indices (Uniprot) | 303-724 (302-722) |
| Mutations (UniProt numbering) | |
| Missing residues | 345GLN-349ARG |
| Structural gaps | Exists |
| Uniprot ID | P29475 ￫UniprotKB |
| label_asym_ids of heme | P |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |
| auth_asym_id | D |
|---|---|
| Residue indices (Uniprot) | 304-722 (302-722) |
| Mutations (UniProt numbering) | |
| Missing residues | 345GLN-353VAL |
| Structural gaps | Exists |
| Uniprot ID | P29475 ￫UniprotKB |
| label_asym_ids of heme | W |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.10 Å |