PDB ID: pdb_00008fgk
- Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(5-(2-(diethylamino)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine
- Experimental method: X-RAY DIFFRACTION
- Resolution: 2.25 Å
- Deposition date: 2022-12-12
Number of assemblies: 2
| Structural data | modeled |
|---|---|
| Oligomeric count | 2 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
F (H4B  H4B
), G (XVF XVF
), H (GOL GOL
), I (ZN ZN
), J (H4BH4B
), L (XVFXVF
), M (GOLGOL
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 303-722 (302-722) |
| Mutations (UniProt numbering) | |
| Uniprot ID | P29475 ￫UniprotKB |
| label_asym_ids of heme | E |
| Available structure | PDB |
| auth_asym_id | B |
|---|---|
| Residue indices (Uniprot) | 304-724 (302-722) |
| Mutations (UniProt numbering) | |
| Missing residues | 345GLN-351GLU |
| Structural gaps | Exists |
| Uniprot ID | P29475 ￫UniprotKB |
| label_asym_ids of heme | K |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.10 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 2 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
O (XVFXVF
), P (GOLGOL
), Q (GOLGOL
), R (ZNZN
), S (H4BH4B
), U (H4BH4B
), V (XVFXVF
), W (GOLGOL
)
|
Each chain information
| auth_asym_id | C |
|---|---|
| Residue indices (Uniprot) | 303-724 (302-722) |
| Mutations (UniProt numbering) | |
| Missing residues | 344SER-351GLU |
| Structural gaps | Exists |
| Uniprot ID | P29475 ￫UniprotKB |
| label_asym_ids of heme | N |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |