PDB ID: pdb_00009cw0
- Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain bound with 6-(5-((3,3-difluoroazetidin-1-yl)methyl)-2,3-difluorophenyl)-4-methylpyridin-2-amine dihydrochloride
- Experimental method: X-RAY DIFFRACTION
- Resolution: 2.1 Å
- Deposition date: 2024-07-29
Number of assemblies: 2
| Structural data | modeled |
|---|---|
| Oligomeric count | 2 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
F (H4B  H4B
), G (A1A A1A
), H (GOL GOL
), I (GOLGOL
), J (ZN ZN
), L (H4BH4B
), M (A1AA1A
), N (GOLGOL
), O (GOLGOL
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 304-722 (302-722) |
| Mutations (UniProt numbering) | |
| Missing residues | 344SER-351GLU |
| Structural gaps | Exists |
| Uniprot ID | P29475 ￫UniprotKB |
| label_asym_ids of heme | E |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.11 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 2 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
Q (H4BH4B
), R (A1AA1A
), S (GOLGOL
), T (GOLGOL
), U (ZNZN
), W (H4BH4B
), X (A1AA1A
), Y (GOLGOL
)
|
Each chain information
| auth_asym_id | C |
|---|---|
| Residue indices (Uniprot) | 304-722 (302-722) |
| Mutations (UniProt numbering) | |
| Uniprot ID | P29475 ￫UniprotKB |
| label_asym_ids of heme | P |
| Available structure | PDB |
| auth_asym_id | D |
|---|---|
| Residue indices (Uniprot) | 304-722 (302-722) |
| Mutations (UniProt numbering) | |
| Missing residues | 345GLN-350PRO |
| Structural gaps | Exists |
| Uniprot ID | P29475 ￫UniprotKB |
| label_asym_ids of heme | V |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.11 Å |