Uniprot ID: A0A2H4A2U9
- Protein: CYP51, sterol 14alpha-demethylase
- Organism: Brain eating amoeba (Naegleria fowleri)
- Length: 466
- Sequence:
MAKKTSSKGKLPPRVPNLIPYVGSFVSFAKNPVQFIIDNSKKYGDVFTATILGKEMTFLNHPKILDTFFKATDNELSLRDVYRFMRPVFGTGVVYDADSTERMMEQVKFVSSGLTTARFRVFVDIFEDEIAHKVKELGPEGTVDVAELMADLIIFTASRCLLGDEVRQYLSEKNLGKLYHDIDDGISPLSFFYPSLPAPKRDKARKAVGEIFQELLDKRREEHKKHPERLLDESKMDVVDHLLTQKYKDGQELTDVHRIGILIAGLFAGQHTSSITSSWTLMNVISNKKVLEKVRKEQEEIMGSDKVLDYDKVMKMDYLEACMKEALRMYPPLIMIMRMARKPRECEQYIIPKGNILVVSPSVAGRCTDTYTNPDVFDPERLTERKEHEKFKYGAVPFGAGRHKCIGENFALLQVKSIISILLRYFDMEYIGKIPDPSYTSLVVGPSPPTRMRYKLRKQQHHHHHH
Number of chains: 12
| Resolution | 1.71 Å |
|---|---|
| Residue indices (Uniprot), coverage | 35-484 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| Missing residues | 371CYS-371CYS:392CYS-392CYS |
| Nonstandard amino acids |
CSO
|
| label_asym_ids of heme | B |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |
| Resolution | 1.76 Å |
|---|---|
| Residue indices (Uniprot), coverage | 35-485 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | B |
| Available structure | PDB |
| Resolution | 1.81 Å |
|---|---|
| Residue indices (Uniprot), coverage | 10-459 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | B |
| Available structure | PDB |
| Resolution | 1.87 Å |
|---|---|
| Residue indices (Uniprot), coverage | 35-483 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| Missing residues | 371CYS-371CYS:392CYS-392CYS |
| Nonstandard amino acids |
CSO
|
| label_asym_ids of heme | B |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |
| Resolution | 2.10 Å |
|---|---|
| Residue indices (Uniprot), coverage | 10-461 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | B |
| Available structure | PDB |
| Resolution | 2.11 Å |
|---|---|
| Residue indices (Uniprot), coverage | 35-483 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | E |
| Available structure | PDB |
| Resolution | 2.11 Å |
|---|---|
| Residue indices (Uniprot), coverage | 35-483 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | B |
| label_asym_ids of heme | G |
| Available structure | PDB |
| Resolution | 2.11 Å |
|---|---|
| Residue indices (Uniprot), coverage | 35-483 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | C |
| label_asym_ids of heme | I |
| Available structure | PDB |
| Resolution | 2.11 Å |
|---|---|
| Residue indices (Uniprot), coverage | 35-483 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | D |
| label_asym_ids of heme | K |
| Available structure | PDB |
| Resolution | 2.40 Å |
|---|---|
| Residue indices (Uniprot), coverage | 35-483 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| Missing residues | 392CYS-392CYS |
| Nonstandard amino acids |
CSO
|
| label_asym_ids of heme | C |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.14 Å |
| Resolution | 2.60 Å |
|---|---|
| Residue indices (Uniprot), coverage | 35-483 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | B |
| Available structure | PDB |
| Resolution | 2.70 Å |
|---|---|
| Residue indices (Uniprot), coverage | 35-484 (1-466), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | B |
| Available structure | PDB |
