Uniprot ID: P00179
- Protein: Cytochrome P450 2C5
- Organism: Rabbit (Oryctolagus cuniculus)
- Length: 487
- Sequence:
MDPVVVLVLGLCCLLLLSIWKQNSGRGKLPPGPTPFPIIGNILQIDAKDISKSLTKFSECYGPVFTVYLGMKPTVVLHGYEAVKEALVDLGEEFAGRGSVPILEKVSKGLGIAFSNAKTWKEMRRFSLMTLRNFGMGKRSIEDRIQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHNRFDYKDEEFLKLMESLNENVRILSSPWLQVYNNFPALLDYFPGIHKTLLKNADYIKNFIMEKVKEHQKLLDVNNPRDFIDCFLIKMEQENNLEFTLESLVIAVSDLFGAGTETTSTTLRYSLLLLLKHPEVAARVQEEIERVIGRHRSPCMQDRSRMPYTDAVIHEIQRFIDLLPTNLPHAVTRDVRFRNYFIPKGTDIITSLTSVLHDEKAFPNPKVFDPGHFLDESGNFKKSDYFMPFSAGKRMCVGEGLARMELFLFLTSILQNFKLQSLVEPKDLDITAVVNGFVSVPPSYQLCFIPI
Number of chains: 3
| Resolution | 2.10 Å |
|---|---|
| Residue indices (Uniprot), coverage | 27-488 (27-487), 0.96 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| Mutations (UniProt numbering) | W20A, Q22K, N23T, G25S, R26K, N202H, R206E, I207L, S209G, S210T |
| Insertions | 487insHHHH |
| Deletions | D2-I19 |
| Sequence identity to UniProt | 0.9787 |
| auth_asym_id | A |
| label_asym_ids of heme | D |
| Available structure | PDB |
| Resolution | 2.30 Å |
|---|---|
| Residue indices (Uniprot), coverage | 27-488 (27-487), 0.96 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| Mutations (UniProt numbering) | W20A, Q22K, N23T, G25S, R26K, N202H, R206E, I207L, S209G, S210T |
| Insertions | 487insHHHH |
| Deletions | D2-I19 |
| Sequence identity to UniProt | 0.9787 |
| auth_asym_id | A |
| label_asym_ids of heme | D |
| Available structure | PDB |
| Resolution | 3.00 Å |
|---|---|
| Residue indices (Uniprot), coverage | 30-489 (21-487), 0.96 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| Mutations (UniProt numbering) | W20A, Q22K, N23T, G25S, R26K, N202H, R206E, I207L, S209G, S210T |
| Insertions | 487insHHHH |
| Deletions | D2-I19 |
| Sequence identity to UniProt | 0.9787 |
| auth_asym_id | A |
| Missing residues | 212TRP-222LEU |
| Structural gaps | Exists |
| label_asym_ids of heme | F |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.18 Å |
