Uniprot ID: P05979
- Protein: Prostaglandin G/H synthase 1
- Organism: Sheep (Ovis aries)
- Length: 600
- Sequence:
MSRQSISLRFPLLLLLLSPSPVFSADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPEIWTWLRTTLRPSPSFIHFLLTHGRWLWDFVNATFIRDTLMRLVLTVRSNLIPSPPTYNIAHDYISWESFSNVSYYTRILPSVPRDCPTPMDTKGKKQLPDAEFLSRRFLLRRKFIPDPQSTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQMLNGEVYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATIWLREHNRVCDLLKAEHPTWGDEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGAQFQYRNRIAMEFNQLYHWHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVEALVDAFSRQPAGRIGGGRNIDHHILHVAVDVIKESRVLRLQPFNEYRKRFGMKPYTSFQELTGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKASTFGGEVGFNLVKTATLKKLVCLNTKTCPYVSFHVPDPRQEDRPGVERPPTEL
Number of chains: 47
| Resolution | 2.00 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | A |
| label_asym_ids of heme | N |
| Available structure | PDB |
| Resolution | 2.00 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | B |
| label_asym_ids of heme | V |
| Available structure | PDB |
| Resolution | 2.40 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-600), 0.95 |
| Difference from Uniprot sequence | SEE REMARK 999 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31 |
| Sequence identity to UniProt | 0.9965 |
| auth_asym_id | A |
| label_asym_ids of heme | G |
| Available structure | PDB |
| Resolution | 2.40 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-600), 0.95 |
| Difference from Uniprot sequence | SEE REMARK 999 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31 |
| Sequence identity to UniProt | 0.9965 |
| auth_asym_id | B |
| label_asym_ids of heme | J |
| Available structure | PDB |
| Resolution | 2.60 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | conflict |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | A |
| label_asym_ids of heme | H |
| Available structure | PDB |
| Resolution | 2.60 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | conflict:microheterogeneity |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | B |
| Missing residues | 530SER-530SER |
| Nonstandard amino acids |
OAS
|
| label_asym_ids of heme | L |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.10 Å |
| Resolution | 2.61 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (21-600), 0.97 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S20 |
| Sequence identity to UniProt | 0.9966 |
| auth_asym_id | A |
| label_asym_ids of heme | J |
| Available structure | PDB |
| Resolution | 2.61 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (21-600), 0.97 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S20 |
| Sequence identity to UniProt | 0.9966 |
| auth_asym_id | B |
| label_asym_ids of heme | R |
| Available structure | PDB |
| Resolution | 2.69 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (33-583), 0.92 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-P32, D584-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | A |
| label_asym_ids of heme | I |
| Available structure | PDB |
| Resolution | 2.69 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (33-583), 0.92 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-P32, D584-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | B |
| label_asym_ids of heme | P |
| Available structure | PDB |
| Resolution | 2.70 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (21-600), 0.97 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S20 |
| Sequence identity to UniProt | 0.9966 |
| auth_asym_id | A |
| label_asym_ids of heme | J |
| Available structure | PDB |
| Resolution | 2.70 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (21-600), 0.97 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S20 |
| Sequence identity to UniProt | 0.9966 |
| auth_asym_id | B |
| label_asym_ids of heme | R |
| Available structure | PDB |
| Resolution | 2.70 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (1-600), 1.00 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 0.9967 |
| auth_asym_id | P |
| label_asym_ids of heme | H |
| Available structure | PDB |
| Resolution | 2.70 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (1-600), 1.00 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 0.9967 |
| auth_asym_id | P |
| label_asym_ids of heme | H-1 |
| Available structure | PDB |
| Resolution | 2.75 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (33-583), 0.92 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-P32, D584-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | A |
| label_asym_ids of heme | I |
| Available structure | PDB |
| Resolution | 2.75 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (33-583), 0.92 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-P32, D584-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | B |
| label_asym_ids of heme | R |
| Available structure | PDB |
| Resolution | 2.75 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | SEE REMARK 999 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | A |
| label_asym_ids of heme | H |
| Available structure | PDB |
| Resolution | 2.75 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | SEE REMARK 999 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | B |
| Structural gaps | Exists |
| label_asym_ids of heme | M |
| Available structure | PDB |
| Resolution | 2.75 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | conflict |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | A |
| label_asym_ids of heme | I |
| Available structure | PDB |
| Resolution | 2.75 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | conflict |
| Mutations (UniProt numbering) | R120Q, D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9946 |
| auth_asym_id | B |
| label_asym_ids of heme | L |
| Available structure | PDB |
| Resolution | 2.75 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | conflict |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | A |
| label_asym_ids of heme | G |
| Available structure | PDB |
| Resolution | 2.75 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | conflict |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | B |
| label_asym_ids of heme | J |
| Available structure | PDB |
| Resolution | 2.75 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (1-600), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | I |
| Available structure | PDB |
| Resolution | 2.75 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (1-600), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | B |
| label_asym_ids of heme | L |
| Available structure | PDB |
| Resolution | 2.85 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (1-600), 1.00 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 0.9967 |
| auth_asym_id | P |
| label_asym_ids of heme | H |
| Available structure | PDB |
| Resolution | 2.85 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (1-600), 1.00 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 0.9967 |
| auth_asym_id | P |
| label_asym_ids of heme | H-1 |
| Available structure | PDB |
| Resolution | 2.90 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | conflict |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | A |
| label_asym_ids of heme | H |
| Available structure | PDB |
| Resolution | 2.90 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | conflict |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | B |
| label_asym_ids of heme | M |
| Available structure | PDB |
| Resolution | 2.93 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (1-600), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | I |
| Available structure | PDB |
| Resolution | 2.93 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (1-600), 1.00 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | None |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | B |
| label_asym_ids of heme | L |
| Available structure | PDB |
| Resolution | 3.05 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | conflict |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | A |
| label_asym_ids of heme | I |
| Available structure | PDB |
| Resolution | 3.05 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Difference from Uniprot sequence | conflict |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | B |
| label_asym_ids of heme | M |
| Available structure | PDB |
| Resolution | 3.10 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-583 (21-600), 0.97 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S20 |
| Sequence identity to UniProt | 0.9966 |
| auth_asym_id | A |
| label_asym_ids of heme | L |
| Available structure | PDB |
| Resolution | 3.10 Å |
|---|---|
| Residue indices (Uniprot), coverage | 31-583 (21-600), 0.97 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S20 |
| Sequence identity to UniProt | 0.9966 |
| auth_asym_id | B |
| label_asym_ids of heme | P |
| Available structure | PDB |
| Resolution | 3.20 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (33-583), 0.92 |
| Difference from Uniprot sequence | conflict:modified residue |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-P32, D584-L600 |
| Sequence identity to UniProt | 0.9964 |
| auth_asym_id | A |
| Missing residues | 530SER-530SER |
| Nonstandard amino acids |
OAS
|
| label_asym_ids of heme | F |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.11 Å |
| Resolution | 3.35 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | I |
| Available structure | PDB |
| Resolution | 3.35 Å |
|---|---|
| Residue indices (Uniprot), coverage | 32-584 (32-584), 0.92 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | M1-A31, P585-L600 |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | B |
| label_asym_ids of heme | K |
| Available structure | PDB |
| Resolution | 3.40 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (25-600), 0.96 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S24 |
| Sequence identity to UniProt | 0.9965 |
| auth_asym_id | A |
| Missing residues | 530SER-530SER |
| Nonstandard amino acids |
0AH
|
| label_asym_ids of heme | H |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.15 Å |
| Resolution | 3.40 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (25-600), 0.96 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S24 |
| Sequence identity to UniProt | 0.9965 |
| auth_asym_id | B |
| Missing residues | 530SER-530SER |
| Nonstandard amino acids |
0AH
|
| label_asym_ids of heme | M |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.15 Å |
| Resolution | 3.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (25-600), 0.96 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S24 |
| Sequence identity to UniProt | 0.9965 |
| auth_asym_id | A |
| label_asym_ids of heme | H |
| Available structure | PDB |
| Resolution | 3.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (25-600), 0.96 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S24 |
| Sequence identity to UniProt | 0.9965 |
| auth_asym_id | B |
| label_asym_ids of heme | M |
| Available structure | PDB |
| Resolution | 3.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-586 (33-586), 0.92 |
| Difference from Uniprot sequence | conflict |
| Mutations (UniProt numbering) | D164G, S193G, N310Q, R333K |
| Insertions | None |
| Deletions | M1-P32, Q587-L600 |
| Sequence identity to UniProt | 0.9928 |
| auth_asym_id | A |
| label_asym_ids of heme | C |
| Available structure | PDB |
| Resolution | 3.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-586 (33-586), 0.92 |
| Difference from Uniprot sequence | conflict |
| Mutations (UniProt numbering) | D164G, S193G, N310Q, R333K |
| Insertions | None |
| Deletions | M1-P32, Q587-L600 |
| Sequence identity to UniProt | 0.9928 |
| auth_asym_id | B |
| label_asym_ids of heme | D |
| Available structure | PDB |
| Resolution | 4.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (25-600), 0.96 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S24 |
| Sequence identity to UniProt | 0.9965 |
| auth_asym_id | A |
| label_asym_ids of heme | G |
| Available structure | PDB |
| Resolution | 4.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (25-600), 0.96 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S24 |
| Sequence identity to UniProt | 0.9965 |
| auth_asym_id | B |
| label_asym_ids of heme | K |
| Available structure | PDB |
| Resolution | 4.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (25-600), 0.96 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S24 |
| Sequence identity to UniProt | 0.9965 |
| auth_asym_id | A |
| label_asym_ids of heme | G |
| Available structure | PDB |
| Resolution | 4.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 33-583 (25-600), 0.96 |
| Mutations (UniProt numbering) | D164G, S193G |
| Insertions | None |
| Deletions | M1-S24 |
| Sequence identity to UniProt | 0.9965 |
| auth_asym_id | B |
| label_asym_ids of heme | K |
| Available structure | PDB |
