- Protein: Cytochrome P450 2C9
- Organism: Human (Homo sapiens)
- Length: 490
- Sequence:
MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV
| Resolution | 2.00 Å |
|---|---|
| Residue indices (Uniprot), coverage | 26-492 (23-490), 0.96 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| auth_asym_id | A |
| Structural gaps | Exists |
| label_asym_ids of heme | B |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.15 Å |
| Resolution | 2.00 Å |
|---|---|
| Residue indices (Uniprot), coverage | 26-492 (23-489), 0.95 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | A |
| Structural gaps | Exists |
| label_asym_ids of heme | C |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.14 Å |
| Resolution | 2.00 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-490 (19-490), 0.96 |
| Difference from Uniprot sequence | See Sequence details:engineered mutation:expression tag |
| auth_asym_id | A |
| label_asym_ids of heme | B |
| Available structure | PDB |
| Resolution | 2.00 Å |
|---|---|
| Residue indices (Uniprot), coverage | 27-490 (18-489), 0.96 |
| Difference from Uniprot sequence | expression tag:initiating methionine |
| auth_asym_id | A |
| label_asym_ids of heme | B |
| Available structure | PDB |
| Resolution | 2.23 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-490 (24-490), 0.95 |
| Difference from Uniprot sequence | engineered mutation:expression tag:initiating methionine:insertion |
| auth_asym_id | A |
| label_asym_ids of heme | B |
| Available structure | PDB |
| Resolution | 2.30 Å |
|---|---|
| Residue indices (Uniprot), coverage | 26-492 (23-489), 0.95 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | A |
| Structural gaps | Exists |
| label_asym_ids of heme | B |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.14 Å |
| Resolution | 2.30 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-490 (28-490), 0.94 |
| Difference from Uniprot sequence | engineered mutation |
| auth_asym_id | A |
| label_asym_ids of heme | E |
| Available structure | PDB |
| Resolution | 2.45 Å |
|---|---|
| Residue indices (Uniprot), coverage | 27-490 (30-490), 0.94 |
| Difference from Uniprot sequence | engineered mutation:expression tag:insertion |
| auth_asym_id | A |
| label_asym_ids of heme | C |
| Available structure | PDB |
| Resolution | 2.45 Å |
|---|---|
| Residue indices (Uniprot), coverage | 27-490 (30-490), 0.94 |
| Difference from Uniprot sequence | engineered mutation:expression tag:insertion |
| auth_asym_id | B |
| label_asym_ids of heme | G |
| Available structure | PDB |
| Resolution | 2.48 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-490 (19-490), 0.96 |
| Difference from Uniprot sequence | See Sequence details:engineered mutation:expression tag |
| auth_asym_id | A |
| label_asym_ids of heme | B |
| Available structure | PDB |
| Resolution | 2.55 Å |
|---|---|
| Residue indices (Uniprot), coverage | 30-490 (19-490), 0.96 |
| Difference from Uniprot sequence | engineered mutation |
| auth_asym_id | A |
| label_asym_ids of heme | C |
| Available structure | PDB |
| Resolution | 2.55 Å |
|---|---|
| Residue indices (Uniprot), coverage | 30-490 (19-490), 0.96 |
| Difference from Uniprot sequence | engineered mutation |
| auth_asym_id | B |
| label_asym_ids of heme | E |
| Available structure | PDB |
| Resolution | 2.60 Å |
|---|---|
| Residue indices (Uniprot), coverage | 30-490 (19-490), 0.96 |
| Difference from Uniprot sequence | engineered mutation |
| auth_asym_id | A |
| label_asym_ids of heme | C |
| Available structure | PDB |
| Resolution | 2.60 Å |
|---|---|
| Residue indices (Uniprot), coverage | 30-490 (19-490), 0.96 |
| Difference from Uniprot sequence | engineered mutation |
| auth_asym_id | B |
| label_asym_ids of heme | D |
| Available structure | PDB |
| Resolution | 2.90 Å |
|---|---|
| Residue indices (Uniprot), coverage | 26-492 (23-489), 0.95 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | A |
| Structural gaps | Exists |
| label_asym_ids of heme | B |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.17 Å |
| Resolution | 3.12 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-490 (19-490), 0.96 |
| Difference from Uniprot sequence | SEE SEQUENCE DETAILS:engineered mutation:initiating methionine |
| auth_asym_id | A |
| Structural gaps | Exists |
| label_asym_ids of heme | I |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.13 Å |
| Resolution | 3.12 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-491 (19-490), 0.96 |
| Difference from Uniprot sequence | SEE SEQUENCE DETAILS:engineered mutation:initiating methionine |
| auth_asym_id | B |
| Structural gaps | Exists |
| label_asym_ids of heme | K |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.14 Å |
| Resolution | 3.12 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-491 (19-490), 0.96 |
| Difference from Uniprot sequence | SEE SEQUENCE DETAILS:engineered mutation:initiating methionine |
| auth_asym_id | C |
| Structural gaps | Exists |
| label_asym_ids of heme | M |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.15 Å |
| Resolution | 3.12 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-491 (19-490), 0.96 |
| Difference from Uniprot sequence | SEE SEQUENCE DETAILS:engineered mutation:initiating methionine |
| auth_asym_id | D |
| Structural gaps | Exists |
| label_asym_ids of heme | O |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.16 Å |
| Resolution | 3.12 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-491 (19-490), 0.96 |
| Difference from Uniprot sequence | SEE SEQUENCE DETAILS:engineered mutation:initiating methionine |
| auth_asym_id | E |
| Structural gaps | Exists |
| label_asym_ids of heme | R |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.15 Å |
| Resolution | 3.12 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-491 (19-490), 0.96 |
| Difference from Uniprot sequence | SEE SEQUENCE DETAILS:engineered mutation:initiating methionine |
| auth_asym_id | F |
| Structural gaps | Exists |
| label_asym_ids of heme | W |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.15 Å |
| Resolution | 3.12 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-490 (19-490), 0.96 |
| Difference from Uniprot sequence | SEE SEQUENCE DETAILS:engineered mutation:initiating methionine |
| auth_asym_id | G |
| Structural gaps | Exists |
| label_asym_ids of heme | BA |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.15 Å |
| Resolution | 3.12 Å |
|---|---|
| Residue indices (Uniprot), coverage | 28-490 (19-490), 0.96 |
| Difference from Uniprot sequence | SEE SEQUENCE DETAILS:engineered mutation:initiating methionine |
| auth_asym_id | H |
| Structural gaps | Exists |
| label_asym_ids of heme | GA |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.15 Å |
| Residue indices (Uniprot), coverage | 28-491 (24-490), 0.95 |
|---|---|
| Difference from Uniprot sequence | engineered mutation:expression tag:initiating methionine:insertion |
| auth_asym_id | A |
| label_asym_ids of heme | E |
| Available structure | PDB |
| Residue indices (Uniprot), coverage | 28-490 (24-490), 0.95 |
|---|---|
| Difference from Uniprot sequence | engineered mutation:expression tag:initiating methionine:insertion |
| auth_asym_id | A |
| label_asym_ids of heme | B |
| Available structure | PDB |