- Protein: Lanosterol 14-alpha demethylase
- Organism: Human (Homo sapiens)
- Length: 509
- Sequence:
MAAAAGMLLLGLLQAGGSVLGQAMEKVTGGNLLSMLLIACAFTLSLVYLIRLAAGHLVQLPAGVKSPPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQKKMLKSGLNIAHFKQHVSIIEKETKEYFESWGESGEKNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQKRRQSQEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPVIRYKRRSK
| Resolution | 1.98 Å |
|---|---|
| Residue indices (Uniprot), coverage | 57-502 (67-509), 0.87 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| auth_asym_id | A |
| label_asym_ids of heme | C |
| Available structure | PDB |
| Resolution | 1.98 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-509), 0.87 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| auth_asym_id | B |
| label_asym_ids of heme | E |
| Available structure | PDB |
| Resolution | 2.04 Å |
|---|---|
| Residue indices (Uniprot), coverage | 61-502 (67-509), 0.87 |
| auth_asym_id | A |
| label_asym_ids of heme | E |
| Available structure | PDB |
| Resolution | 2.04 Å |
|---|---|
| Residue indices (Uniprot), coverage | 61-502 (67-509), 0.87 |
| auth_asym_id | B |
| label_asym_ids of heme | H |
| Available structure | PDB |
| Resolution | 2.04 Å |
|---|---|
| Residue indices (Uniprot), coverage | 61-502 (67-509), 0.87 |
| auth_asym_id | C |
| label_asym_ids of heme | K |
| Available structure | PDB |
| Resolution | 2.04 Å |
|---|---|
| Residue indices (Uniprot), coverage | 61-502 (67-509), 0.87 |
| auth_asym_id | D |
| label_asym_ids of heme | N |
| Available structure | PDB |
| Resolution | 2.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-509), 0.87 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | A |
| label_asym_ids of heme | I |
| Available structure | PDB |
| Resolution | 2.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-509), 0.87 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | B |
| label_asym_ids of heme | L |
| Available structure | PDB |
| Resolution | 2.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-509), 0.87 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | C |
| label_asym_ids of heme | O |
| Available structure | PDB |
| Resolution | 2.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-509), 0.87 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | D |
| label_asym_ids of heme | R |
| Available structure | PDB |
| Resolution | 2.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-509), 0.87 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | E |
| label_asym_ids of heme | U |
| Available structure | PDB |
| Resolution | 2.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-509), 0.87 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | F |
| label_asym_ids of heme | X |
| Available structure | PDB |
| Resolution | 2.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-509), 0.87 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | G |
| label_asym_ids of heme | AA |
| Available structure | PDB |
| Resolution | 2.50 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-509), 0.87 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | H |
| label_asym_ids of heme | DA |
| Available structure | PDB |
| Resolution | 2.73 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-508), 0.87 |
| Difference from Uniprot sequence | engineered mutation:expression tag:initiating methionine |
| auth_asym_id | A |
| label_asym_ids of heme | C |
| Available structure | PDB |
| Resolution | 2.73 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-508), 0.87 |
| Difference from Uniprot sequence | engineered mutation:expression tag:initiating methionine |
| auth_asym_id | B |
| label_asym_ids of heme | D |
| Available structure | PDB |
| Resolution | 2.80 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (60-508), 0.88 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | A |
| label_asym_ids of heme | E |
| Available structure | PDB |
| Resolution | 2.80 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-501 (60-508), 0.88 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | B |
| label_asym_ids of heme | G |
| Available structure | PDB |
| Resolution | 2.80 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (67-509), 0.87 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | A |
| label_asym_ids of heme | C |
| Available structure | PDB |
| Resolution | 2.80 Å |
|---|---|
| Residue indices (Uniprot), coverage | 59-502 (67-509), 0.87 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | B |
| label_asym_ids of heme | N |
| Available structure | PDB |
| Resolution | 2.90 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (60-508), 0.88 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | A |
| label_asym_ids of heme | F |
| Available structure | PDB |
| Resolution | 2.90 Å |
|---|---|
| Residue indices (Uniprot), coverage | 58-502 (60-508), 0.88 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | B |
| label_asym_ids of heme | I |
| Available structure | PDB |
| Resolution | 3.12 Å |
|---|---|
| Residue indices (Uniprot), coverage | 55-502 (60-508), 0.88 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | A |
| label_asym_ids of heme | C |
| Available structure | PDB |
| Resolution | 3.12 Å |
|---|---|
| Residue indices (Uniprot), coverage | 55-502 (60-508), 0.88 |
| Difference from Uniprot sequence | expression tag |
| auth_asym_id | A |
| label_asym_ids of heme | C-1 |
| Available structure | PDB |
| Residue indices (Uniprot), coverage | 57-502 (67-509), 0.87 |
|---|---|
| Difference from Uniprot sequence | engineered mutation:expression tag |
| auth_asym_id | A |
| label_asym_ids of heme | C |
| Available structure | PDB |
| Residue indices (Uniprot), coverage | 57-502 (67-509), 0.87 |
|---|---|
| Difference from Uniprot sequence | engineered mutation:expression tag |
| auth_asym_id | B |
| Structural gaps | Exists |
| label_asym_ids of heme | E |
| Available structure | PDB and Modeled |
| RMSD of modeled structure from PDB structure | 0.15 Å |