Danish
PDB ID:  pdb_00003tik
  • Sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei in complex with the tipifarnib derivative 6-((4-chlorophenyl)(methoxy)(1-methyl-1H-imidazol-5-yl)methyl)-4-(2,6-difluorophenyl)-1-methylquinolin-2(1H)-one
  • Experimental method: X-RAY DIFFRACTION
  • Resolution: 2.05 Å
  • Deposition date: 2011-08-20
Number of assemblies:  1
Assembly ID:  1  (author_defined_assembly)    
Structural data PDB
Oligomeric count 4
label_asym_ids of protein
label_asym_ids of heme
label_asym_ids of the others F (JKFStructure of JKFJKF ), H (JKFStructure of JKFJKF ), J (JKFStructure of JKFJKF ), L (JKFStructure of JKFJKF )
Each chain information
Chain A heme  
auth_asym_id A
Residue indices (Uniprot) 28-477 (32-481)
Mutations (UniProt numbering)
Uniprot ID Q385E8 ￫UniprotKB
label_asym_ids of heme E
Available structure PDB
Chain B heme  
auth_asym_id B
Residue indices (Uniprot) 28-477 (32-481)
Mutations (UniProt numbering)
Uniprot ID Q385E8 ￫UniprotKB
label_asym_ids of heme G
Available structure PDB
Chain C heme  
auth_asym_id C
Residue indices (Uniprot) 28-477 (32-481)
Mutations (UniProt numbering)
Uniprot ID Q385E8 ￫UniprotKB
label_asym_ids of heme I
Available structure PDB
Chain D heme  
auth_asym_id D
Residue indices (Uniprot) 28-477 (32-481)
Mutations (UniProt numbering)
Uniprot ID Q385E8 ￫UniprotKB
label_asym_ids of heme K
Available structure PDB