PDB ID: pdb_00004c28
- Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(4-chlorophenyl)piperazin-1-yl)-2-fluorobenzamide.
- Experimental method: X-RAY DIFFRACTION
- Resolution: 2.03 Å
- Deposition date: 2013-08-16
Number of assemblies: 2
| Structural data | modeled |
|---|---|
| Oligomeric count | 1 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
D (TW5  TW5
), E (EDO EDO
), F (CL CL
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 29-477 (29-481) |
| Mutations (UniProt numbering) | |
| Missing residues | 252ALA-257ASN |
| Structural gaps | Exists |
| Uniprot ID | Q7Z1V1 ￫UniprotKB |
| label_asym_ids of heme | C |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.13 Å |
| Structural data | modeled |
|---|---|
| Oligomeric count | 1 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
H (TW5TW5
)
|
Each chain information
| auth_asym_id | B |
|---|---|
| Residue indices (Uniprot) | 29-476 (29-481) |
| Mutations (UniProt numbering) | |
| Missing residues | 252ALA-258THR |
| Structural gaps | Exists |
| Uniprot ID | Q7Z1V1 ￫UniprotKB |
| label_asym_ids of heme | G |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.13 Å |