PDB ID: pdb_00004uqh
- Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(3,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide.
- Experimental method: X-RAY DIFFRACTION
- Resolution: 2.43 Å
- Deposition date: 2014-06-23
Number of assemblies: 1
| Structural data | modeled |
|---|---|
| Oligomeric count | 3 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
C (SO4  SO4
), C-1 (SO4SO4
), C-2 (SO4SO4
), D (SO4SO4
), D-1 (SO4SO4
), D-2 (SO4SO4
), E (SO4SO4
), E-1 (SO4SO4
), E-2 (SO4SO4
), F (SO4SO4
), F-1 (SO4SO4
), F-2 (SO4SO4
), G (SO4SO4
), G-1 (SO4SO4
), G-2 (SO4SO4
), H (SO4SO4
), H-1 (SO4SO4
), H-2 (SO4SO4
), I (SO4SO4
), I-1 (SO4SO4
), I-2 (SO4SO4
), J (25S 25S
), J-1 (25S25S
), J-2 (25S25S
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 28-477 (32-481) |
| Mutations (UniProt numbering) | |
| Missing residues | 251GLU-257ASN |
| Structural gaps | Exists |
| Uniprot ID | Q7Z1V1 ￫UniprotKB |
| label_asym_ids of heme | B |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.13 Å |
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 28-477 (32-481) |
| Mutations (UniProt numbering) | |
| Missing residues | 251GLU-257ASN |
| Structural gaps | Exists |
| Uniprot ID | Q7Z1V1 ￫UniprotKB |
| label_asym_ids of heme | B-1 |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 28-477 (32-481) |
| Mutations (UniProt numbering) | |
| Missing residues | 251GLU-257ASN |
| Structural gaps | Exists |
| Uniprot ID | Q7Z1V1 ￫UniprotKB |
| label_asym_ids of heme | B-2 |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.13 Å |