PDB ID: pdb_00005ajr
- Sterol 14-alpha demethylase (CYP51) from Trypanosoma cruzi in complex with the 1-tetrazole derivative VT-1161 ((R)-2-(2,4-Difluorophenyl)-1, 1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl) pyridin-2-yl)propan-2-ol)
- Experimental method: X-RAY DIFFRACTION
- Resolution: 2.75 Å
- Deposition date: 2015-02-26
Number of assemblies: 1
| Structural data | modeled |
|---|---|
| Oligomeric count | 1 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
C (VT1  VT1
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 29-478 (32-481) |
| Mutations (UniProt numbering) | |
| Missing residues | 222PRO-222PRO |
| Structural gaps | Exists |
| Uniprot ID | Q7Z1V1 ￫UniprotKB |
| label_asym_ids of heme | B |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.18 Å |