PDB ID: pdb_00006pyy
- Crystal Structure of human Tryptophan 2,3-dioxygenase in complex with PF-06840003 in Active Site and Exo site
- Experimental method: X-RAY DIFFRACTION
- Resolution: 2.4 Å
- Deposition date: 2019-07-31
Number of assemblies: 1
| Structural data | modeled |
|---|---|
| Oligomeric count | 4 |
| label_asym_ids of protein | |
| label_asym_ids of heme | |
| label_asym_ids of the others |
F (H7S  H7S
), G (H7SH7S
), I (H7SH7S
), J (H7SH7S
), L (H7SH7S
), M (H7SH7S
), O (H7SH7S
), P (H7SH7S
)
|
Each chain information
| auth_asym_id | A |
|---|---|
| Residue indices (Uniprot) | 38-388 (18-389) |
| Mutations (UniProt numbering) | |
| Uniprot ID | P48775 ￫UniprotKB |
| label_asym_ids of heme | E |
| Available structure | PDB |
| auth_asym_id | B |
|---|---|
| Residue indices (Uniprot) | 38-381 (18-389) |
| Mutations (UniProt numbering) | |
| Missing residues | 177ARG-178ARG |
| Structural gaps | Exists |
| Uniprot ID | P48775 ￫UniprotKB |
| label_asym_ids of heme | H |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.12 Å |
| auth_asym_id | C |
|---|---|
| Residue indices (Uniprot) | 39-391 (18-389) |
| Mutations (UniProt numbering) | |
| Missing residues | 175TYR-178ARG:237GLU-253GLN |
| Structural gaps | Exists |
| Uniprot ID | P48775 ￫UniprotKB |
| label_asym_ids of heme | K |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.16 Å |
| auth_asym_id | D |
|---|---|
| Residue indices (Uniprot) | 39-391 (18-389) |
| Mutations (UniProt numbering) | |
| Missing residues | 340ALA-345SER |
| Structural gaps | Exists |
| Uniprot ID | P48775 ￫UniprotKB |
| label_asym_ids of heme | N |
| Available structure | PDB and Modeled |
| RMSD of experimental residues after energy minimization | 0.11 Å |