Danish
Uniprot ID:  A0ABU7R6J9
  • Protein: DNA polymerase I
  • Organism: Chryseobacterium arthrosphaerae
  • Length: 1002
  • Sequence:
    • MGSSHHHHHHSSGLVPRGSHMKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITENLYFQGMISYDNYVTILDEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRERALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRVYTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPDVLEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPLLVEVGSGENWDQAH
Exclude chains with
Mutations (vs. UniProt)
Clear
Number of chains:  3
PDB ID:  pdb_000021oo , Chain A 
Resolution 2.55 Å
Residue indices (Uniprot), coverage 0-762 (497-497), 0.74
Difference from Uniprot sequence conflict:engineered mutation:expression tag:initiating methionine
Mutations (UniProt numbering) L14E, V15N, P16L, R17Y, G18F, S19Q, H20G, A333V, I512T, F514V, D515P, T516L, M517S, I522H, L523I, N524S, S525E, V526E, A527Y, R529F, H530L, D531L, M532P, A536K, E566P, E567D, A568H, G569Y, Y571P, A572W, A573M, D575I, D577N, V578K, T579L, L580P, H583I, L584D, K585A, M586H, W587Q, P588L, D589Q, L590A, Q591H, K592V, H593D, G595M, N598E, V599A, F600Q, E601P, N602A, I603E, E604V, M605L, L607R, V608N, P609L, V610A, S612P, R613F, I614V, R616V, N617S, G618R, V619N, K620L, I621G, D622L, K624P, V625I, H627V, N628Y, H629S, S630D, E631L, E632V, L635N, R636W, L637T, A638K, E639K, L640D, E641P, K642D, K643G, A644F, H645L, A648G, G649N, E650L, F652T, N653I, L654I, S656F, T657P, K658G, Q659G, L660E, Q661S, T662L, I663H, L664G, E666I, K667L, Q668V, G669T, I670A, K671L, P672V, L673E, K675E, T676A, P677V, G678P, A680I, P681K, S682A, T683L, S684V, E685Q, E686A, V687T, L688N, E689A, E690I, D694L, Y695Q, P696A, P698Q, K699R, V700L, I701R, E703S, Y704I, R705Q, G706D, L707I, A708T, L710T, K711L, S712G, T713Q, Y714M, T715H, K717Y, L718V, P719D, L720P, M721D, N723F, P724Y, K725A, T726G, G727I, V729I, Y730F, T731L, R761W, R762K, I763D, R764N, Q765P, F767M, I768P, P770G, E771L, D772M, V774E, I775G, A802Q, G804P, K805L, D806K, I807Y, H808S, R809G, A810G, T811S, E814Q, V815S, F816T, G817V, P819H, L820A, E821F, T822D, V823E, T824F, S825L, E826G, Q827I, R829H, A831K, K832E, A833S, I834G, N835D, G837L, L838Y, I839R, Y840M, G841R, M842D, S843Y, A844M, F845P, G846P, L847S, A848H, R849K, Q850A, L851F, N852I, I853E, P854D, R855I, K856H, E857S, Q859P, K860S, Y861L, M862R, L864Y, Y865I, F866L, E867S, R868S, Y869G, P870Q, V872H, E874L, Y875T, M876A, E877Y, R878N, T879Q, R880C, A881V, K884L, E885A, Q886E, G887L, Y888R, V889S, E890Y, T891H, L892I, D893T, G894M, R895V, R896T, L897K, Q923I, G924T, T925A, D928K, I929A, I930K, K931H, R932G, A933K, M934P, I935N, A936H, V937L, D938P, A939G, W940P, L941P, E944L, Q945K, P946D, V948G, R949T, M950G, I951G, M952T, Q953A, H955M, D956S, E957F, V959K, F960S, E961V, V962R, H963D, G993T, S994L, G995E, E996S, N997I, W998L, D999H, Q1000P, A1001R, H1002G
Insertions 597insLSCQFLKGHREQRLAHLVLSFLTMGYVWQEG, 691insQPNQE
Deletions S11-G13, R388-G511, R538-A564, Y733-E759, A778-F801, P900-M922, D965-V992
Sequence identity to UniProt 0.6005
auth_asym_id A
Missing residues 722GLY-734LEU
Structural gaps Exists
label_asym_ids of heme D
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.12 Å
PDB ID:  pdb_000021ok , Chain A 
Resolution 2.60 Å
Residue indices (Uniprot), coverage 0-762 (497-497), 0.74
Difference from Uniprot sequence conflict:engineered mutation:expression tag:initiating methionine
Mutations (UniProt numbering) L14E, V15N, P16L, R17Y, G18F, S19Q, H20G, A333V, I512T, F514V, D515P, T516L, M517S, I522H, L523I, N524S, S525E, V526E, A527Y, R529F, H530L, D531L, M532P, A536K, E566P, E567D, A568H, G569Y, Y571P, A572W, A573M, D575I, D577N, V578K, T579L, L580P, H583I, L584D, K585A, M586H, W587Q, P588L, D589Q, L590A, Q591H, K592V, H593D, G595M, N598E, V599A, F600Q, E601P, N602A, I603E, E604V, M605L, L607R, V608N, P609L, V610A, S612P, R613F, I614V, R616V, N617S, G618R, V619N, K620L, I621G, D622L, K624P, V625I, H627V, N628Y, H629S, S630D, E631L, E632V, L635N, R636W, L637T, A638K, E639K, L640D, E641P, K642D, K643G, A644F, H645L, A648G, G649N, E650L, F652T, N653I, L654I, S656F, T657P, K658G, Q659G, L660E, Q661S, T662L, I663H, L664G, E666I, K667L, Q668V, G669T, I670A, K671L, P672V, L673E, K675E, T676A, P677V, G678P, A680I, P681K, S682A, T683L, S684V, E685Q, E686A, V687T, L688N, E689A, E690I, D694L, Y695Q, P696A, P698Q, K699R, V700L, I701R, E703S, Y704I, R705Q, G706D, L707I, A708T, L710T, K711L, S712G, T713Q, Y714M, T715H, K717Y, L718V, P719D, L720P, M721D, N723F, P724Y, K725A, T726G, G727I, V729I, Y730F, T731L, R761W, R762K, I763D, R764N, Q765P, F767M, I768P, P770G, E771L, D772M, V774E, I775G, A802Q, G804P, K805L, D806K, I807Y, H808S, R809G, A810G, T811S, E814Q, V815S, F816T, G817V, P819H, L820A, E821F, T822D, V823E, T824F, S825L, E826G, Q827I, R829H, A831K, K832E, A833S, I834G, N835D, G837L, L838Y, I839R, Y840M, G841R, M842D, S843Y, A844M, F845P, G846P, L847S, A848H, R849K, Q850A, L851F, N852I, I853E, P854D, R855I, K856H, E857S, Q859P, K860S, Y861L, M862R, L864Y, Y865I, F866L, E867S, R868S, Y869G, P870Q, V872H, E874L, Y875T, M876A, E877Y, R878N, T879Q, R880C, A881V, K884L, E885A, Q886E, G887L, Y888R, V889S, E890Y, T891H, L892I, D893T, G894M, R895V, R896T, L897K, Q923I, G924T, T925A, D928K, I929A, I930K, K931H, R932G, A933K, M934P, I935N, A936H, V937L, D938P, A939G, W940P, L941P, E944L, Q945K, P946D, V948G, R949T, M950G, I951G, M952T, Q953A, H955M, D956S, E957F, V959K, F960S, E961V, V962R, H963D, G993T, S994L, G995E, E996S, N997I, W998L, D999H, Q1000P, A1001R, H1002G
Insertions 597insLSCQFLKGHREQRLAHLVLSFLTMGYVWQEG, 691insQPNQE
Deletions S11-G13, R388-G511, R538-A564, Y733-E759, A778-F801, P900-M922, D965-V992
Sequence identity to UniProt 0.6005
auth_asym_id A
Missing residues 722GLY-735LYS
Structural gaps Exists
label_asym_ids of heme J
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.12 Å
PDB ID:  pdb_000021om , Chain A 
Resolution 2.68 Å
Residue indices (Uniprot), coverage 0-762 (21-387), 0.74
Difference from Uniprot sequence conflict:expression tag:initiating methionine
Mutations (UniProt numbering) L14E, V15N, P16L, R17Y, G18F, S19Q, H20G, A333V, I512T, F514V, D515P, T516L, M517S, I522H, L523I, N524S, S525E, V526E, A527Y, R529F, H530L, D531L, M532P, A536K, E566P, E567D, A568H, G569Y, Y571P, A572W, A573M, D575I, D577N, V578K, T579L, L580P, H583I, L584D, K585A, M586H, W587Q, P588L, D589Q, L590A, Q591H, K592V, H593D, G595M, N598E, V599A, F600Q, E601P, N602A, I603E, E604V, M605L, L607R, V608N, P609L, V610A, S612P, R613F, I614V, R616V, N617S, G618R, V619N, K620L, I621G, D622L, K624P, V625I, H627V, N628H, H629S, S630D, E631L, E632V, L635N, R636W, L637T, A638K, E639K, L640D, E641P, K642D, K643G, A644F, H645L, A648G, G649N, E650L, F652T, N653I, L654I, S656F, T657P, K658G, Q659G, L660E, Q661S, T662L, I663H, L664G, E666I, K667L, Q668V, G669T, I670A, K671L, P672V, L673E, K675E, T676A, P677V, G678P, A680I, P681K, S682A, T683L, S684V, E685Q, E686A, V687T, L688N, E689A, E690I, D694L, Y695Q, P696A, P698Q, K699R, V700L, I701R, E703S, Y704I, R705Q, G706D, L707I, A708T, L710T, K711L, S712G, T713Q, Y714M, T715H, K717Y, L718V, P719D, L720P, M721D, N723F, P724Y, K725A, T726G, G727I, V729I, Y730F, T731L, R761W, R762K, I763D, R764N, Q765P, F767M, I768P, P770G, E771L, D772M, V774E, I775G, A802Q, G804P, K805L, D806K, I807Y, H808S, R809G, A810G, T811S, E814Q, V815S, F816T, G817V, P819H, L820A, E821F, T822D, V823E, T824F, S825L, E826G, Q827I, R829H, A831K, K832E, A833S, I834G, N835D, G837L, L838Y, I839R, Y840M, G841R, M842D, S843Y, A844M, F845P, G846P, L847S, A848H, R849K, Q850A, L851F, N852I, I853E, P854D, R855I, K856H, E857S, Q859P, K860S, Y861L, M862R, L864Y, Y865I, F866L, E867S, R868S, Y869G, P870Q, V872H, E874L, Y875T, M876A, E877Y, R878N, T879Q, R880C, A881V, K884L, E885A, Q886E, G887L, Y888R, V889S, E890Y, T891H, L892I, D893T, G894M, R895V, R896T, L897K, Q923I, G924T, T925A, D928K, I929A, I930K, K931H, R932G, A933K, M934P, I935N, A936H, V937L, D938P, A939G, W940P, L941P, E944L, Q945K, P946D, V948G, R949T, M950G, I951G, M952T, Q953A, H955M, D956S, E957F, V959K, F960S, E961V, V962R, H963D, G993T, S994L, G995E, E996S, N997I, W998L, D999H, Q1000P, A1001R, H1002G
Insertions 597insLSCQFLKGHREQRLAHLVLSFLTMGYVWQEG, 691insQPNQE
Deletions S11-G13, R388-G511, R538-A564, Y733-E759, A778-F801, P900-M922, D965-V992
Sequence identity to UniProt 0.6005
auth_asym_id A
Missing residues 722GLY-737ARG
Structural gaps Exists
label_asym_ids of heme D
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.12 Å