Danish
Uniprot ID:  O08394
  • Protein: Bifunctional cytochrome P450/NADPH--P450 reductase 1
  • Organism: Bacillus subtilis (strain 168)
  • Length: 1061
  • Sequence:
    • MKETSPIPQPKTFGPLGNLPLIDKDKPTLSLIKLAEEQGPIFQIHTPAGTTIVVSGHELVKEVCDEERFDKSIEGALEKVRAFSGDGLFTSWTHEPNWRKAHNILMPTFSQRAMKDYHEKMVDIAVQLIQKWARLNPNEAVDVPGDMTRLTLDTIGLCGFNYRFNSYYRETPHPFINSMVRALDEAMHQMQRLDVQDKLMVRTKRQFRYDIQTMFSLVDSIIAERRANGDQDEKDLLARMLNVEDPETGEKLDDENIRFQIITFLIAGHETTSGLLSFATYFLLKHPDKLKKAYEEVDRVLTDAAPTYKQVLELTYIRMILNESLRLWPTAPAFSLYPKEDTVIGGKFPITTNDRISVLIPQLHRDRDAWGKDAEEFRPERFEHQDQVPHHAYKPFGNGQRACIGMQFALHEATLVLGMILKYFTLIDHENYELDIKQTLTLKPGDFHISVQSRHQEAIHADVQAAEKAAPDEQKEKTEAKGASVIGLNNRPLLVLYGSDTGTAEGVARELADTASLHGVRTKTAPLNDRIGKLPKEGAVVIVTSSYNGKPPSNAGQFVQWLQEIKPGELEGVHYAVFGCGDHNWASTYQYVPRFIDEQLAEKGATRFSARGEGDVSGDFEGQLDEWKKSMWADAIKAFGLELNENADKERSTLSLQFVRGLGESPLARSYEASHASIAENRELQSADSDRSTRHIEIALPPDVEYQEGDHLGVLPKNSQTNVSRILHRFGLKGTDQVTLSASGRSAGHLPLGRPVSLHDLLSYSVEVQEAATRAQIRELASFTVCPPHRRELEELSAEGVYQEQILKKRISMLDLLEKYEACDMPFERFLELLRPLKPRYYSISSSPRVNPRQASITVGVVRGPAWSGRGEYRGVASNDLAERQAGDDVVMFIRTPESRFQLPKDPETPIIMVGPGTGVAPFRGFLQARDVLKREGKTLGEAHLYFGCRNDRDFIYRDELERFEKDGIVTVHTAFSRKEGMPKTYVQHLMADQADTLISILDRGGRLYVCGDGSKMAPDVEAALQKAYQAVHGTGEQEAQNWLRHLQDTGMYAKDVWAGI
Exclude chains with
Mutations (vs. UniProt)
Clear
Number of chains:  10
PDB ID:  pdb_00009wuk , Chain A 
Resolution 2.34 Å
Residue indices (Uniprot), coverage 5-1036 (354-1061), 0.98
Mutations (UniProt numbering) K2D, T4A, S5N, P6I, F13Y, L19I, T28I, L31F, I32M, Q38Y, Q43R, I44L, H45Q, A48G, G49D, T50S, E67S, D70L, I73A, A76P, S84G, E119D, K120M, A133I, N138D, A140T, G145D, N177T, M190T, V195L, V201I, R208Q, Y209H, T213V, N228G, G229K, D230N, D232K, K234N, A238S, E244S, F259Y, T280L, H286N, R299Q, D303G, A304S, A305T, E313H, T315K, I317V, S324A, P338A, V343I, F348Y, I350K, T351K, T352E, N353Q, D354E, S357T, R367K, D368E, K372E, A374V, H384D, D386N, Q387K, I420L, K422R, Y423H, T425E, L426F, H429Y, E430K, N431D, E433Q, H448N, S450Q, S453P, H455N, E457P, V485F, I486Q, V507I, S516T, R521H, K523E, T524V, P526T, D529E, K533E, V541L, Q563E, E564A, I565V, K566Q, P567A, E571S, H574Q, Y591D, E598K, T606V, G622E, L624F, E626Q, K629E, S630K, A633S, K637E, L643I, N644S, E645D, N646D, A647V, D648K, E650D, R651Q, S652N, R660K, L662T, E664G, S674V, H675Y, S677K, I678V, A679V, A687P, D690G, A699T, P702K, D703G, E705S, K717A, Q720K, T721E, S724H, I726V, H728Q, R729K, F730Y, G731K, K733N, G734E, T735N, T739V, S741T, A747M, G748A, G753A, R754Q, P755E, H759R, S763L, V768L, E770D, S782A, R790K, E795A, S797L, A798E, V801I, I806V, D824E, R835H, V850L, P852S, R853E, Q854R, G860A, R870L, D880Y, E883D, R884C, Q885K, A886P, D888E, V891M, R900N, K905E, D906E, P907S, V920L, V932A, L933M, R935Q, H944Y, D952E, R953A, D959K, R963Q, F964Y, E965K, D967N, V970M, V972L, H973Y, T974I, M982I, L990V, D993S, Q994N, D996E, T997S, S1000R, R1004Q, V1010I, K1016R, D1020E, A1024T, Q1026K, K1027N, A1028S, A1031E, T1035A, Q1041S, N1042Q, R1045E, H1046K, D1049K, T1050D, M1052Q, I1061L
Insertions 349insV
Deletions I459-S484
Sequence identity to UniProt 0.7845
auth_asym_id A
Missing residues 457GLN-464ASN
Structural gaps Exists
label_asym_ids of heme C
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.13 Å
PDB ID:  pdb_00009wuk , Chain B 
Resolution 2.34 Å
Residue indices (Uniprot), coverage 5-1036 (1-353), 0.98
Mutations (UniProt numbering) K2D, T4A, S5N, P6I, F13Y, L19I, T28I, L31F, I32M, Q38Y, Q43R, I44L, H45Q, A48G, G49D, T50S, E67S, D70L, I73A, A76P, S84G, E119D, K120M, A133I, N138D, A140T, G145D, N177T, M190T, V195L, V201I, R208Q, Y209H, T213V, N228G, G229K, D230N, D232K, K234N, A238S, E244S, F259Y, T280L, H286N, R299Q, D303G, A304S, A305T, E313H, T315K, I317V, S324A, P338A, V343I, F348Y, I350K, T351K, T352E, N353Q, D354E, S357T, R367K, D368E, K372E, A374V, H384D, D386N, Q387K, I420L, K422R, Y423H, T425E, L426F, H429Y, E430K, N431D, E433Q, H448N, S450Q, S453P, H455N, E457P, V485F, I486Q, V507I, S516T, R521H, K523E, T524V, P526T, D529E, K533E, V541L, Q563E, E564A, I565V, K566Q, P567A, E571S, H574Q, Y591D, E598K, T606V, G622E, L624F, E626Q, K629E, S630K, A633S, K637E, L643I, N644S, E645D, N646D, A647V, D648K, E650D, R651Q, S652N, R660K, L662T, E664G, S674V, H675Y, S677K, I678V, A679V, A687P, D690G, A699T, P702K, D703G, E705S, K717A, Q720K, T721E, S724H, I726V, H728Q, R729K, F730Y, G731K, K733N, G734E, T735N, T739V, S741T, A747M, G748A, G753A, R754Q, P755E, H759R, S763L, V768L, E770D, S782A, R790K, E795A, S797L, A798E, V801I, I806V, D824E, R835H, V850L, P852S, R853E, Q854R, G860A, R870L, D880Y, E883D, R884C, Q885K, A886P, D888E, V891M, R900N, K905E, D906E, P907S, V920L, V932A, L933M, R935Q, H944Y, D952E, R953A, D959K, R963Q, F964Y, E965K, D967N, V970M, V972L, H973Y, T974I, M982I, L990V, D993S, Q994N, D996E, T997S, S1000R, R1004Q, V1010I, K1016R, D1020E, A1024T, Q1026K, K1027N, A1028S, A1031E, T1035A, Q1041S, N1042Q, R1045E, H1046K, D1049K, T1050D, M1052Q, I1061L
Insertions 349insV
Deletions I459-S484
Sequence identity to UniProt 0.7845
auth_asym_id B
Missing residues 457GLN-462GLY
Structural gaps Exists
label_asym_ids of heme F
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.12 Å
PDB ID:  pdb_00009wup , Chain A 
Resolution 2.68 Å
Residue indices (Uniprot), coverage 5-1067 (354-482), 1.00
Mutations (UniProt numbering) K2D, T4A, S5N, P6I, F13Y, L19I, T28I, L31F, I32M, Q38Y, Q43R, I44L, H45Q, A48G, G49D, T50S, E67S, D70L, I73A, A76P, S84G, E119D, K120M, A133I, N138D, A140T, G145D, N177T, M190T, V195L, V201I, R208Q, Y209H, T213V, N228G, G229K, D230N, D232K, K234N, A238S, E244S, F259Y, T280L, H286N, R299Q, D303G, A304S, A305T, E313H, T315K, I317V, S324A, P338A, V343I, F348Y, I350K, T351K, T352E, N353Q, D354E, S357T, R367K, D368E, K372E, A374V, H384D, D386N, Q387K, I420L, K422R, Y423H, T425E, L426F, H429Y, E430K, N431D, E433Q, H448N, S450Q, S453P, H455N, E457P, I459F, H460Q, A461Q, D462S, Q464V, K468S, A469K, A470M, P471E, D472M, E473K, K475V, E476K, K477D, T478H, E479F, A480D, K481Q, G482K, A483S, S484T, V485I, I486Q, V507I, S516T, R521H, K523E, T524V, P526T, D529E, K533E, V541L, Q563E, E564A, I565V, K566Q, P567A, E571S, H574Q, Y591D, E598K, T606V, G622E, L624F, E626Q, K629E, S630K, A633S, K637E, L643I, N644S, E645D, N646D, A647V, D648K, E650D, R651Q, S652N, R660K, L662T, E664G, S674V, H675Y, S677K, I678V, A679V, A687P, D690G, A699T, P702K, D703G, E705S, K717A, Q720K, T721E, S724H, I726V, H728Q, R729K, F730Y, G731K, K733N, G734E, T735N, T739V, S741T, A747M, G748A, G753A, R754Q, P755E, H759R, S763L, V768L, E770D, S782A, R790K, E795A, S797L, A798E, V801I, I806V, D824E, R835H, V850L, P852S, R853E, Q854R, G860A, R870L, D880Y, E883D, R884C, Q885K, A886P, D888E, V891M, R900N, K905E, D906E, P907S, V920L, V932A, L933M, R935Q, H944Y, D952E, R953A, D959K, R963Q, F964Y, E965K, D967N, V970M, V972L, H973Y, T974I, M982I, L990V, D993S, Q994N, D996E, T997S, S1000R, R1004Q, V1010I, K1016R, D1020E, A1024T, Q1026K, K1027N, A1028S, A1031E, T1035A, Q1041S, N1042Q, R1045E, H1046K, D1049K, T1050D, M1052Q, I1061L
Insertions 349insV, 463insSVTED
Deletions None
Sequence identity to UniProt 0.7700
auth_asym_id A
Structural gaps Exists
label_asym_ids of heme C
Available structure PDB
PDB ID:  pdb_00009wup , Chain B 
Resolution 2.68 Å
Residue indices (Uniprot), coverage 5-1067 (1-353), 1.00
Mutations (UniProt numbering) K2D, T4A, S5N, P6I, F13Y, L19I, T28I, L31F, I32M, Q38Y, Q43R, I44L, H45Q, A48G, G49D, T50S, E67S, D70L, I73A, A76P, S84G, E119D, K120M, A133I, N138D, A140T, G145D, N177T, M190T, V195L, V201I, R208Q, Y209H, T213V, N228G, G229K, D230N, D232K, K234N, A238S, E244S, F259Y, T280L, H286N, R299Q, D303G, A304S, A305T, E313H, T315K, I317V, S324A, P338A, V343I, F348Y, I350K, T351K, T352E, N353Q, D354E, S357T, R367K, D368E, K372E, A374V, H384D, D386N, Q387K, I420L, K422R, Y423H, T425E, L426F, H429Y, E430K, N431D, E433Q, H448N, S450Q, S453P, H455N, E457P, I459F, H460Q, A461Q, D462S, Q464V, K468S, A469K, A470M, P471E, D472M, E473K, K475V, E476K, K477D, T478H, E479F, A480D, K481Q, G482K, A483S, S484T, V485I, I486Q, V507I, S516T, R521H, K523E, T524V, P526T, D529E, K533E, V541L, Q563E, E564A, I565V, K566Q, P567A, E571S, H574Q, Y591D, E598K, T606V, G622E, L624F, E626Q, K629E, S630K, A633S, K637E, L643I, N644S, E645D, N646D, A647V, D648K, E650D, R651Q, S652N, R660K, L662T, E664G, S674V, H675Y, S677K, I678V, A679V, A687P, D690G, A699T, P702K, D703G, E705S, K717A, Q720K, T721E, S724H, I726V, H728Q, R729K, F730Y, G731K, K733N, G734E, T735N, T739V, S741T, A747M, G748A, G753A, R754Q, P755E, H759R, S763L, V768L, E770D, S782A, R790K, E795A, S797L, A798E, V801I, I806V, D824E, R835H, V850L, P852S, R853E, Q854R, G860A, R870L, D880Y, E883D, R884C, Q885K, A886P, D888E, V891M, R900N, K905E, D906E, P907S, V920L, V932A, L933M, R935Q, H944Y, D952E, R953A, D959K, R963Q, F964Y, E965K, D967N, V970M, V972L, H973Y, T974I, M982I, L990V, D993S, Q994N, D996E, T997S, S1000R, R1004Q, V1010I, K1016R, D1020E, A1024T, Q1026K, K1027N, A1028S, A1031E, T1035A, Q1041S, N1042Q, R1045E, H1046K, D1049K, T1050D, M1052Q, I1061L
Insertions 349insV, 463insSVTED
Deletions None
Sequence identity to UniProt 0.7700
auth_asym_id B
Structural gaps Exists
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00009wuc , Chain A 
Resolution 2.72 Å
Residue indices (Uniprot), coverage 5-1067 (483-1061), 1.00
Mutations (UniProt numbering) K2D, T4A, S5N, P6I, F13Y, L19I, T28I, L31F, I32M, Q38Y, Q43R, I44L, H45Q, A48G, G49D, T50S, E67S, D70L, I73A, A76P, S84G, E119D, K120M, A133I, N138D, A140T, G145D, N177T, M190T, V195L, V201I, R208Q, Y209H, T213V, N228G, G229K, D230N, D232K, K234N, A238S, E244S, F259Y, T280L, H286N, R299Q, D303G, A304S, A305T, E313H, T315K, I317V, S324A, P338A, V343I, F348Y, I350K, T351K, T352E, N353Q, D354E, S357T, R367K, D368E, K372E, A374V, H384D, D386N, Q387K, I420L, K422R, Y423H, T425E, L426F, H429Y, E430K, N431D, E433Q, H448N, S450Q, S453P, H455N, E457P, I459F, H460Q, A461Q, D462S, Q464V, K468S, A469K, A470M, P471E, D472M, E473K, K475V, E476K, K477D, T478H, E479F, A480D, K481Q, G482K, A483S, S484T, V485I, I486Q, V507I, S516T, R521H, K523E, T524V, P526T, D529E, K533E, V541L, Q563E, E564A, I565V, K566Q, P567A, E571S, H574Q, Y591D, E598K, T606V, G622E, L624F, E626Q, K629E, S630K, A633S, K637E, L643I, N644S, E645D, N646D, A647V, D648K, E650D, R651Q, S652N, R660K, L662T, E664G, S674V, H675Y, S677K, I678V, A679V, A687P, D690G, A699T, P702K, D703G, E705S, K717A, Q720K, T721E, S724H, I726V, H728Q, R729K, F730Y, G731K, K733N, G734E, T735N, T739V, S741T, A747M, G748A, G753A, R754Q, P755E, H759R, S763L, V768L, E770D, S782A, R790K, E795A, S797L, A798E, V801I, I806V, D824E, R835H, V850L, P852S, R853E, Q854R, G860A, R870L, D880Y, E883D, R884C, Q885K, A886P, D888E, V891M, R900N, K905E, D906E, P907S, V920L, V932A, L933M, R935Q, H944Y, D952E, R953A, D959K, R963Q, F964Y, E965K, D967N, V970M, V972L, H973Y, T974I, M982I, L990V, D993S, Q994N, D996E, T997S, S1000R, R1004Q, V1010I, K1016R, D1020E, A1024T, Q1026K, K1027N, A1028S, A1031E, T1035A, Q1041S, N1042Q, R1045E, H1046K, D1049K, T1050D, M1052Q, I1061L
Insertions 349insV, 463insSVTED
Deletions None
Sequence identity to UniProt 0.7700
auth_asym_id A
Structural gaps Exists
label_asym_ids of heme C
Available structure PDB
PDB ID:  pdb_00009wuc , Chain B 
Resolution 2.72 Å
Residue indices (Uniprot), coverage 5-1067 (354-482), 1.00
Mutations (UniProt numbering) K2D, T4A, S5N, P6I, F13Y, L19I, T28I, L31F, I32M, Q38Y, Q43R, I44L, H45Q, A48G, G49D, T50S, E67S, D70L, I73A, A76P, S84G, E119D, K120M, A133I, N138D, A140T, G145D, N177T, M190T, V195L, V201I, R208Q, Y209H, T213V, N228G, G229K, D230N, D232K, K234N, A238S, E244S, F259Y, T280L, H286N, R299Q, D303G, A304S, A305T, E313H, T315K, I317V, S324A, P338A, V343I, F348Y, I350K, T351K, T352E, N353Q, D354E, S357T, R367K, D368E, K372E, A374V, H384D, D386N, Q387K, I420L, K422R, Y423H, T425E, L426F, H429Y, E430K, N431D, E433Q, H448N, S450Q, S453P, H455N, E457P, I459F, H460Q, A461Q, D462S, Q464V, K468S, A469K, A470M, P471E, D472M, E473K, K475V, E476K, K477D, T478H, E479F, A480D, K481Q, G482K, A483S, S484T, V485I, I486Q, V507I, S516T, R521H, K523E, T524V, P526T, D529E, K533E, V541L, Q563E, E564A, I565V, K566Q, P567A, E571S, H574Q, Y591D, E598K, T606V, G622E, L624F, E626Q, K629E, S630K, A633S, K637E, L643I, N644S, E645D, N646D, A647V, D648K, E650D, R651Q, S652N, R660K, L662T, E664G, S674V, H675Y, S677K, I678V, A679V, A687P, D690G, A699T, P702K, D703G, E705S, K717A, Q720K, T721E, S724H, I726V, H728Q, R729K, F730Y, G731K, K733N, G734E, T735N, T739V, S741T, A747M, G748A, G753A, R754Q, P755E, H759R, S763L, V768L, E770D, S782A, R790K, E795A, S797L, A798E, V801I, I806V, D824E, R835H, V850L, P852S, R853E, Q854R, G860A, R870L, D880Y, E883D, R884C, Q885K, A886P, D888E, V891M, R900N, K905E, D906E, P907S, V920L, V932A, L933M, R935Q, H944Y, D952E, R953A, D959K, R963Q, F964Y, E965K, D967N, V970M, V972L, H973Y, T974I, M982I, L990V, D993S, Q994N, D996E, T997S, S1000R, R1004Q, V1010I, K1016R, D1020E, A1024T, Q1026K, K1027N, A1028S, A1031E, T1035A, Q1041S, N1042Q, R1045E, H1046K, D1049K, T1050D, M1052Q, I1061L
Insertions 349insV, 463insSVTED
Deletions None
Sequence identity to UniProt 0.7700
auth_asym_id B
Structural gaps Exists
label_asym_ids of heme F
Available structure PDB
PDB ID:  pdb_00009wud , Chain A 
Resolution 3.08 Å
Residue indices (Uniprot), coverage 494-1067 (354-482), 1.00
Mutations (UniProt numbering) K2D, T4A, S5N, P6I, F13Y, L19I, T28I, L31F, I32M, Q38Y, Q43R, I44L, H45Q, A48G, G49D, T50S, E67S, D70L, I73A, A76P, S84G, E119D, K120M, A133I, N138D, A140T, G145D, N177T, M190T, V195L, V201I, R208Q, Y209H, T213V, N228G, G229K, D230N, D232K, K234N, A238S, E244S, F259Y, T280L, H286N, R299Q, D303G, A304S, A305T, E313H, T315K, I317V, S324A, P338A, V343I, F348Y, I350K, T351K, T352E, N353Q, D354E, S357T, R367K, D368E, K372E, A374V, H384D, D386N, Q387K, I420L, K422R, Y423H, T425E, L426F, H429Y, E430K, N431D, E433Q, H448N, S450Q, S453P, H455N, E457P, I459F, H460Q, A461Q, D462S, Q464V, K468S, A469K, A470M, P471E, D472M, E473K, K475V, E476K, K477D, T478H, E479F, A480D, K481Q, G482K, A483S, S484T, V485I, I486Q, V507I, S516T, R521H, K523E, T524V, P526T, D529E, K533E, V541L, Q563E, E564A, I565V, K566Q, P567A, E571S, H574Q, Y591D, E598K, T606V, G622E, L624F, E626Q, K629E, S630K, A633S, K637E, L643I, N644S, E645D, N646D, A647V, D648K, E650D, R651Q, S652N, R660K, L662T, E664G, S674V, H675Y, S677K, I678V, A679V, A687P, D690G, A699T, P702K, D703G, E705S, K717A, Q720K, T721E, S724H, I726V, H728Q, R729K, F730Y, G731K, K733N, G734E, T735N, T739V, S741T, A747M, G748A, G753A, R754Q, P755E, H759R, S763L, V768L, E770D, S782A, R790K, E795A, S797L, A798E, V801I, I806V, D824E, R835H, V850L, P852S, R853E, Q854R, G860A, R870L, D880Y, E883D, R884C, Q885K, A886P, D888E, V891M, R900N, K905E, D906E, P907S, V920L, V932A, L933M, R935Q, H944Y, D952E, R953A, D959K, R963Q, F964Y, E965K, D967N, V970M, V972L, H973Y, T974I, M982I, L990V, D993S, Q994N, D996E, T997S, S1000R, R1004Q, V1010I, K1016R, D1020E, A1024T, Q1026K, K1027N, A1028S, A1031E, T1035A, Q1041S, N1042Q, R1045E, H1046K, D1049K, T1050D, M1052Q, I1061L
Insertions 349insV, 463insSVTED
Deletions None
Sequence identity to UniProt 0.7700
auth_asym_id A
label_asym_ids of heme None
Available structure PDB
PDB ID:  pdb_00009wud , Chain B 
Resolution 3.08 Å
Residue indices (Uniprot), coverage 5-1067 (354-482), 1.00
Mutations (UniProt numbering) K2D, T4A, S5N, P6I, F13Y, L19I, T28I, L31F, I32M, Q38Y, Q43R, I44L, H45Q, A48G, G49D, T50S, E67S, D70L, I73A, A76P, S84G, E119D, K120M, A133I, N138D, A140T, G145D, N177T, M190T, V195L, V201I, R208Q, Y209H, T213V, N228G, G229K, D230N, D232K, K234N, A238S, E244S, F259Y, T280L, H286N, R299Q, D303G, A304S, A305T, E313H, T315K, I317V, S324A, P338A, V343I, F348Y, I350K, T351K, T352E, N353Q, D354E, S357T, R367K, D368E, K372E, A374V, H384D, D386N, Q387K, I420L, K422R, Y423H, T425E, L426F, H429Y, E430K, N431D, E433Q, H448N, S450Q, S453P, H455N, E457P, I459F, H460Q, A461Q, D462S, Q464V, K468S, A469K, A470M, P471E, D472M, E473K, K475V, E476K, K477D, T478H, E479F, A480D, K481Q, G482K, A483S, S484T, V485I, I486Q, V507I, S516T, R521H, K523E, T524V, P526T, D529E, K533E, V541L, Q563E, E564A, I565V, K566Q, P567A, E571S, H574Q, Y591D, E598K, T606V, G622E, L624F, E626Q, K629E, S630K, A633S, K637E, L643I, N644S, E645D, N646D, A647V, D648K, E650D, R651Q, S652N, R660K, L662T, E664G, S674V, H675Y, S677K, I678V, A679V, A687P, D690G, A699T, P702K, D703G, E705S, K717A, Q720K, T721E, S724H, I726V, H728Q, R729K, F730Y, G731K, K733N, G734E, T735N, T739V, S741T, A747M, G748A, G753A, R754Q, P755E, H759R, S763L, V768L, E770D, S782A, R790K, E795A, S797L, A798E, V801I, I806V, D824E, R835H, V850L, P852S, R853E, Q854R, G860A, R870L, D880Y, E883D, R884C, Q885K, A886P, D888E, V891M, R900N, K905E, D906E, P907S, V920L, V932A, L933M, R935Q, H944Y, D952E, R953A, D959K, R963Q, F964Y, E965K, D967N, V970M, V972L, H973Y, T974I, M982I, L990V, D993S, Q994N, D996E, T997S, S1000R, R1004Q, V1010I, K1016R, D1020E, A1024T, Q1026K, K1027N, A1028S, A1031E, T1035A, Q1041S, N1042Q, R1045E, H1046K, D1049K, T1050D, M1052Q, I1061L
Insertions 349insV, 463insSVTED
Deletions None
Sequence identity to UniProt 0.7700
auth_asym_id B
Structural gaps Exists
label_asym_ids of heme E
Available structure PDB
PDB ID:  pdb_00009x0n , Chain A 
Resolution 3.38 Å
Residue indices (Uniprot), coverage 5-1067 (354-482), 1.00
Mutations (UniProt numbering) K2D, T4A, S5N, P6I, F13Y, L19I, T28I, L31F, I32M, Q38Y, Q43R, I44L, H45Q, A48G, G49D, T50S, E67S, D70L, I73A, A76P, S84G, E119D, K120M, A133I, N138D, A140T, G145D, N177T, M190T, V195L, V201I, R208Q, Y209H, T213V, N228G, G229K, D230N, D232K, K234N, A238S, E244S, F259Y, T280L, H286N, R299Q, D303G, A304S, A305T, E313H, T315K, I317V, S324A, P338A, V343I, F348Y, I350K, T351K, T352E, N353Q, D354E, S357T, R367K, D368E, K372E, A374V, H384D, D386N, Q387K, I420L, K422R, Y423H, T425E, L426F, H429Y, E430K, N431D, E433Q, H448N, S450Q, S453P, H455N, E457P, I459F, H460Q, A461Q, D462S, Q464V, K468S, A469K, A470M, P471E, D472M, E473K, K475V, E476K, K477D, T478H, E479F, A480D, K481Q, G482K, A483S, S484T, V485I, I486Q, V507I, S516T, R521H, K523E, T524V, P526T, D529E, K533E, V541L, Q563E, E564A, I565V, K566Q, P567A, E571S, H574Q, Y591D, E598K, T606V, G622E, L624F, E626Q, K629E, S630K, A633S, K637E, L643I, N644S, E645D, N646D, A647V, D648K, E650D, R651Q, S652N, R660K, L662T, E664G, S674V, H675Y, S677K, I678V, A679V, A687P, D690G, A699T, P702K, D703G, E705S, K717A, Q720K, T721E, S724H, I726V, H728Q, R729K, F730Y, G731K, K733N, G734E, T735N, T739V, S741T, A747M, G748A, G753A, R754Q, P755E, H759R, S763L, V768L, E770D, S782A, R790K, E795A, S797L, A798E, V801I, I806V, D824E, R835H, V850L, P852S, R853E, Q854R, G860A, R870L, D880Y, E883D, R884C, Q885K, A886P, D888E, V891M, R900N, K905E, D906E, P907S, V920L, V932A, L933M, R935Q, H944Y, D952E, R953A, D959K, R963Q, F964Y, E965K, D967N, V970M, V972L, H973Y, T974I, M982I, L990V, D993S, Q994N, D996E, T997S, S1000R, R1004Q, V1010I, K1016R, D1020E, A1024T, Q1026K, K1027N, A1028S, A1031E, T1035A, Q1041S, N1042Q, R1045E, H1046K, D1049K, T1050D, M1052Q, I1061L
Insertions 349insV, 463insSVTED
Deletions None
Sequence identity to UniProt 0.7700
auth_asym_id A
Structural gaps Exists
label_asym_ids of heme C
Available structure PDB
PDB ID:  pdb_00009x0n , Chain B 
Resolution 3.38 Å
Residue indices (Uniprot), coverage 5-1067 (1-353), 1.00
Mutations (UniProt numbering) K2D, T4A, S5N, P6I, F13Y, L19I, T28I, L31F, I32M, Q38Y, Q43R, I44L, H45Q, A48G, G49D, T50S, E67S, D70L, I73A, A76P, S84G, E119D, K120M, A133I, N138D, A140T, G145D, N177T, M190T, V195L, V201I, R208Q, Y209H, T213V, N228G, G229K, D230N, D232K, K234N, A238S, E244S, F259Y, T280L, H286N, R299Q, D303G, A304S, A305T, E313H, T315K, I317V, S324A, P338A, V343I, F348Y, I350K, T351K, T352E, N353Q, D354E, S357T, R367K, D368E, K372E, A374V, H384D, D386N, Q387K, I420L, K422R, Y423H, T425E, L426F, H429Y, E430K, N431D, E433Q, H448N, S450Q, S453P, H455N, E457P, I459F, H460Q, A461Q, D462S, Q464V, K468S, A469K, A470M, P471E, D472M, E473K, K475V, E476K, K477D, T478H, E479F, A480D, K481Q, G482K, A483S, S484T, V485I, I486Q, V507I, S516T, R521H, K523E, T524V, P526T, D529E, K533E, V541L, Q563E, E564A, I565V, K566Q, P567A, E571S, H574Q, Y591D, E598K, T606V, G622E, L624F, E626Q, K629E, S630K, A633S, K637E, L643I, N644S, E645D, N646D, A647V, D648K, E650D, R651Q, S652N, R660K, L662T, E664G, S674V, H675Y, S677K, I678V, A679V, A687P, D690G, A699T, P702K, D703G, E705S, K717A, Q720K, T721E, S724H, I726V, H728Q, R729K, F730Y, G731K, K733N, G734E, T735N, T739V, S741T, A747M, G748A, G753A, R754Q, P755E, H759R, S763L, V768L, E770D, S782A, R790K, E795A, S797L, A798E, V801I, I806V, D824E, R835H, V850L, P852S, R853E, Q854R, G860A, R870L, D880Y, E883D, R884C, Q885K, A886P, D888E, V891M, R900N, K905E, D906E, P907S, V920L, V932A, L933M, R935Q, H944Y, D952E, R953A, D959K, R963Q, F964Y, E965K, D967N, V970M, V972L, H973Y, T974I, M982I, L990V, D993S, Q994N, D996E, T997S, S1000R, R1004Q, V1010I, K1016R, D1020E, A1024T, Q1026K, K1027N, A1028S, A1031E, T1035A, Q1041S, N1042Q, R1045E, H1046K, D1049K, T1050D, M1052Q, I1061L
Insertions 349insV, 463insSVTED
Deletions None
Sequence identity to UniProt 0.7700
auth_asym_id B
Structural gaps Exists
label_asym_ids of heme F
Available structure PDB