Uniprot ID:  P0AA89
  • Protein: Diguanylate cyclase DosC
  • Organism: Escherichia coli (strain K12)
  • Length: 460
  • Sequence:
  • MEMYFKRMKDEWTGLVEQADPPIRAKAAEIAVAHAHYLSIEFYRIVRIDPHAEEFLSNEQVERQLKSAMERWIINVLSAQVDDVERLIQIQHTVAEVHARIGIPVEIVEMGFRVLKKILYPVIFSSDYSAAEKLQVYHFSINSIDIAMEVMTRAFTFSDSSASKEDENYRIFSLLENAEEEKERQIASILSWEIDIIYKILLDSDLGSSLPLSQADFGLWFNHKGRHYFSGIAEVGHISRLIQDFDGIFNQTMRNTRNLNNRSLRVKFLLQIRNTVSQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDVDKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLRTAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNRVELWKASL
Exclude chains with
Mutations (vs. UniProt)
Number of chains:  6
PDB ID:  pdb_00004zva , Chain A 
Resolution 2.00 Å
Residue indices (Uniprot), coverage 6-154 (8-170), 0.36
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) K6G, R7A
Insertions None
Deletions M1-F5, I171-L460
Sequence identity to UniProt 0.9879
auth_asym_id A
label_asym_ids of heme C
Available structure PDB
PDB ID:  pdb_00004zva , Chain B 
Resolution 2.00 Å
Residue indices (Uniprot), coverage 6-154 (8-170), 0.36
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) K6G, R7A
Insertions None
Deletions M1-F5, I171-L460
Sequence identity to UniProt 0.9879
auth_asym_id B
label_asym_ids of heme D
Available structure PDB
PDB ID:  pdb_00004zvb , Chain A 
Resolution 2.40 Å
Residue indices (Uniprot), coverage 5-154 (1-155), 0.35
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) V453L, L455H, W456H, K457H, A458H, S459H, L460H
Insertions None
Deletions T156-R452
Sequence identity to UniProt 0.9571
auth_asym_id A
label_asym_ids of heme E
Available structure PDB
PDB ID:  pdb_00004zvb , Chain B 
Resolution 2.40 Å
Residue indices (Uniprot), coverage 6-154 (1-155), 0.35
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) V453L, L455H, W456H, K457H, A458H, S459H, L460H
Insertions None
Deletions T156-R452
Sequence identity to UniProt 0.9571
auth_asym_id B
label_asym_ids of heme F
Available structure PDB
PDB ID:  pdb_00004zvb , Chain C 
Resolution 2.40 Å
Residue indices (Uniprot), coverage 5-154 (1-155), 0.35
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) V453L, L455H, W456H, K457H, A458H, S459H, L460H
Insertions None
Deletions T156-R452
Sequence identity to UniProt 0.9571
auth_asym_id C
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00004zvb , Chain D 
Resolution 2.40 Å
Residue indices (Uniprot), coverage 6-154 (1-155), 0.35
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) V453L, L455H, W456H, K457H, A458H, S459H, L460H
Insertions None
Deletions T156-R452
Sequence identity to UniProt 0.9571
auth_asym_id D
label_asym_ids of heme H
Available structure PDB