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Uniprot ID:  P10632
  • Protein: Cytochrome P450 2C8
  • Organism: Human (Homo sapiens)
  • Length: 490
  • Sequence:
    • MEPFVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV
Exclude chains with
Mutations (vs. UniProt)
Clear
Number of chains:  7
PDB ID:  pdb_00002nnj , Chain A 
Resolution 2.28 Å
Residue indices (Uniprot), coverage 28-490 (28-490), 0.96
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) W20A, R21K, Q22K, S23T, C24S, R25S, R26K, R27G
Insertions 490insHHHH
Deletions E2-L19
Sequence identity to UniProt 0.9831
auth_asym_id A
label_asym_ids of heme E
Available structure PDB
PDB ID:  pdb_00002nnh , Chain A 
Resolution 2.60 Å
Residue indices (Uniprot), coverage 28-490 (28-490), 0.96
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) W20A, R21K, Q22K, S23T, C24S, R25S, R26K, R27G
Insertions 490insHHHH
Deletions E2-L19
Sequence identity to UniProt 0.9831
auth_asym_id A
label_asym_ids of heme D
Available structure PDB
PDB ID:  pdb_00002nnh , Chain B 
Resolution 2.60 Å
Residue indices (Uniprot), coverage 28-490 (28-490), 0.96
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) W20A, R21K, Q22K, S23T, C24S, R25S, R26K, R27G
Insertions 490insHHHH
Deletions E2-L19
Sequence identity to UniProt 0.9831
auth_asym_id B
label_asym_ids of heme I
Available structure PDB
PDB ID:  pdb_00001pq2 , Chain A 
Resolution 2.70 Å
Residue indices (Uniprot), coverage 28-490 (28-490), 0.96
Difference from Uniprot sequence engineered mutation:expression tag
Mutations (UniProt numbering) W20A, R21K, Q22K, S23T, C24S, R25S, R26K, R27G
Insertions 490insHHHH
Deletions E2-L19
Sequence identity to UniProt 0.9831
auth_asym_id A
label_asym_ids of heme D
Available structure PDB
PDB ID:  pdb_00001pq2 , Chain B 
Resolution 2.70 Å
Residue indices (Uniprot), coverage 28-490 (28-490), 0.96
Difference from Uniprot sequence engineered mutation:expression tag
Mutations (UniProt numbering) W20A, R21K, Q22K, S23T, C24S, R25S, R26K, R27G
Insertions 490insHHHH
Deletions E2-L19
Sequence identity to UniProt 0.9831
auth_asym_id B
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00002vn0 , Chain A 
Resolution 2.70 Å
Residue indices (Uniprot), coverage 28-491 (19-490), 0.96
Mutations (UniProt numbering) W20A, R21K, Q22K, S23T, C24S, R25S, R26K, R27G
Insertions 490insHHHH
Deletions E2-L19
Sequence identity to UniProt 0.9831
auth_asym_id A
label_asym_ids of heme B
Available structure PDB
PDB ID:  pdb_00002nni , Chain A 
Resolution 2.80 Å
Residue indices (Uniprot), coverage 28-490 (28-490), 0.96
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) W20A, R21K, Q22K, S23T, C24S, R25S, R26K, R27G
Insertions 490insHHHH
Deletions E2-L19
Sequence identity to UniProt 0.9831
auth_asym_id A
label_asym_ids of heme C
Available structure PDB