Danish
Uniprot ID:  P11509
  • Protein: Cytochrome P450 2A6
  • Organism: Human (Homo sapiens)
  • Length: 494
  • Sequence:
    • MLASGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLPR
Exclude chains with
Mutations (vs. UniProt)
Clear
Number of chains:  46
PDB ID:  pdb_00002fdv , Chain A 
Resolution 1.65 Å
Residue indices (Uniprot), coverage 30-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id A
label_asym_ids of heme H
Available structure PDB
PDB ID:  pdb_00002fdv , Chain B 
Resolution 1.65 Å
Residue indices (Uniprot), coverage 32-496 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id B
label_asym_ids of heme L
Available structure PDB
PDB ID:  pdb_00002fdv , Chain C 
Resolution 1.65 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id C
label_asym_ids of heme O
Available structure PDB
PDB ID:  pdb_00002fdv , Chain D 
Resolution 1.65 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id D
label_asym_ids of heme V
Available structure PDB
PDB ID:  pdb_00002fdu , Chain A 
Resolution 1.85 Å
Residue indices (Uniprot), coverage 30-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id A
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00002fdu , Chain B 
Resolution 1.85 Å
Residue indices (Uniprot), coverage 32-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id B
label_asym_ids of heme I
Available structure PDB
PDB ID:  pdb_00002fdu , Chain C 
Resolution 1.85 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id C
label_asym_ids of heme K
Available structure PDB
PDB ID:  pdb_00002fdu , Chain D 
Resolution 1.85 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id D
label_asym_ids of heme M
Available structure PDB
PDB ID:  pdb_00001z10 , Chain A 
Resolution 1.90 Å
Residue indices (Uniprot), coverage 30-494 (25-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id A
label_asym_ids of heme E
Available structure PDB
PDB ID:  pdb_00001z10 , Chain B 
Resolution 1.90 Å
Residue indices (Uniprot), coverage 32-496 (25-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id B
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00001z10 , Chain C 
Resolution 1.90 Å
Residue indices (Uniprot), coverage 31-494 (25-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id C
label_asym_ids of heme J
Available structure PDB
PDB ID:  pdb_00001z10 , Chain D 
Resolution 1.90 Å
Residue indices (Uniprot), coverage 31-494 (25-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id D
label_asym_ids of heme L
Available structure PDB
PDB ID:  pdb_00002fdy , Chain A 
Resolution 1.95 Å
Residue indices (Uniprot), coverage 30-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id A
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00002fdy , Chain B 
Resolution 1.95 Å
Residue indices (Uniprot), coverage 32-495 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id B
label_asym_ids of heme J
Available structure PDB
PDB ID:  pdb_00002fdy , Chain C 
Resolution 1.95 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id C
label_asym_ids of heme L
Available structure PDB
PDB ID:  pdb_00002fdy , Chain D 
Resolution 1.95 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id D
label_asym_ids of heme N
Available structure PDB
PDB ID:  pdb_00001z11 , Chain A 
Resolution 2.05 Å
Residue indices (Uniprot), coverage 30-496 (25-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id A
label_asym_ids of heme E
Available structure PDB
PDB ID:  pdb_00001z11 , Chain B 
Resolution 2.05 Å
Residue indices (Uniprot), coverage 32-495 (25-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id B
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00001z11 , Chain C 
Resolution 2.05 Å
Residue indices (Uniprot), coverage 31-494 (25-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id C
label_asym_ids of heme I
Available structure PDB
PDB ID:  pdb_00001z11 , Chain D 
Resolution 2.05 Å
Residue indices (Uniprot), coverage 31-494 (25-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id D
label_asym_ids of heme K
Available structure PDB
PDB ID:  pdb_00002fdw , Chain A 
Resolution 2.05 Å
Residue indices (Uniprot), coverage 30-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id A
label_asym_ids of heme E
Available structure PDB
PDB ID:  pdb_00002fdw , Chain B 
Resolution 2.05 Å
Residue indices (Uniprot), coverage 32-496 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id B
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00002fdw , Chain C 
Resolution 2.05 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id C
label_asym_ids of heme I
Available structure PDB
PDB ID:  pdb_00002fdw , Chain D 
Resolution 2.05 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence cloning artifact:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id D
label_asym_ids of heme K
Available structure PDB
PDB ID:  pdb_00003t3q , Chain A 
Resolution 2.10 Å
Residue indices (Uniprot), coverage 32-494 (29-494), 0.96
Difference from Uniprot sequence engineered mutation:expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S, I208S, I300F, G301A, S369G
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9809
auth_asym_id A
label_asym_ids of heme E
Available structure PDB
PDB ID:  pdb_00003t3q , Chain B 
Resolution 2.10 Å
Residue indices (Uniprot), coverage 32-494 (29-494), 0.96
Difference from Uniprot sequence engineered mutation:expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S, I208S, I300F, G301A, S369G
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9809
auth_asym_id B
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00003t3q , Chain C 
Resolution 2.10 Å
Residue indices (Uniprot), coverage 32-494 (29-494), 0.96
Difference from Uniprot sequence engineered mutation:expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S, I208S, I300F, G301A, S369G
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9809
auth_asym_id C
label_asym_ids of heme I
Available structure PDB
PDB ID:  pdb_00003t3q , Chain D 
Resolution 2.10 Å
Residue indices (Uniprot), coverage 32-494 (29-494), 0.96
Difference from Uniprot sequence engineered mutation:expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S, I208S, I300F, G301A, S369G
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9809
auth_asym_id D
label_asym_ids of heme K
Available structure PDB
PDB ID:  pdb_00003ebs , Chain A 
Resolution 2.15 Å
Residue indices (Uniprot), coverage 30-494 (29-494), 0.96
Difference from Uniprot sequence engineered mutation:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S, I208S, I300F, G301A, S369G
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9809
auth_asym_id A
label_asym_ids of heme E
Available structure PDB
PDB ID:  pdb_00003ebs , Chain B 
Resolution 2.15 Å
Residue indices (Uniprot), coverage 31-496 (29-494), 0.96
Difference from Uniprot sequence engineered mutation:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S, I208S, I300F, G301A, S369G
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9809
auth_asym_id B
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00003ebs , Chain C 
Resolution 2.15 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence engineered mutation:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S, I208S, I300F, G301A, S369G
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9809
auth_asym_id C
label_asym_ids of heme I
Available structure PDB
PDB ID:  pdb_00003ebs , Chain D 
Resolution 2.15 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence engineered mutation:expression tag
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S, I208S, I300F, G301A, S369G
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9809
auth_asym_id D
label_asym_ids of heme J
Available structure PDB
PDB ID:  pdb_00004ejj , Chain A 
Resolution 2.30 Å
Residue indices (Uniprot), coverage 30-494 (29-494), 0.96
Difference from Uniprot sequence expression tag:initiating methionine:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id A
label_asym_ids of heme E
Available structure PDB
PDB ID:  pdb_00004ejj , Chain B 
Resolution 2.30 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence expression tag:initiating methionine:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id B
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00004ejj , Chain C 
Resolution 2.30 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence expression tag:initiating methionine:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id C
label_asym_ids of heme I
Available structure PDB
PDB ID:  pdb_00004ejj , Chain D 
Resolution 2.30 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence expression tag:initiating methionine:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id D
label_asym_ids of heme L
Available structure PDB
PDB ID:  pdb_00003t3r , Chain A 
Resolution 2.40 Å
Residue indices (Uniprot), coverage 32-494 (29-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id A
label_asym_ids of heme E
Available structure PDB
PDB ID:  pdb_00003t3r , Chain B 
Resolution 2.40 Å
Residue indices (Uniprot), coverage 32-494 (29-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id B
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00003t3r , Chain C 
Resolution 2.40 Å
Residue indices (Uniprot), coverage 32-494 (29-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id C
label_asym_ids of heme I
Available structure PDB
PDB ID:  pdb_00003t3r , Chain D 
Resolution 2.40 Å
Residue indices (Uniprot), coverage 32-495 (29-494), 0.96
Difference from Uniprot sequence expression tag:SEE REMARK 999
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id D
label_asym_ids of heme K
Available structure PDB
PDB ID:  pdb_00004rui , Chain A 
Resolution 2.61 Å
Residue indices (Uniprot), coverage 31-495 (29-494), 0.96
Difference from Uniprot sequence expression tag:variant
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id D
label_asym_ids of heme G
Available structure PDB
PDB ID:  pdb_00004rui , Chain B 
Resolution 2.61 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence expression tag:variant
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id A
label_asym_ids of heme J
Available structure PDB
PDB ID:  pdb_00004rui , Chain C 
Resolution 2.61 Å
Residue indices (Uniprot), coverage 31-495 (29-494), 0.96
Difference from Uniprot sequence expression tag:variant
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id B
label_asym_ids of heme K
Available structure PDB
PDB ID:  pdb_00004rui , Chain D 
Resolution 2.61 Å
Residue indices (Uniprot), coverage 31-494 (29-494), 0.96
Difference from Uniprot sequence expression tag:variant
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id C
label_asym_ids of heme M
Available structure PDB
PDB ID:  pdb_00004rui , Chain E 
Resolution 2.61 Å
Residue indices (Uniprot), coverage 31-495 (29-494), 0.96
Difference from Uniprot sequence expression tag:variant
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id E
label_asym_ids of heme O
Available structure PDB
PDB ID:  pdb_00004rui , Chain F 
Resolution 2.61 Å
Residue indices (Uniprot), coverage 31-495 (29-494), 0.96
Difference from Uniprot sequence expression tag:variant
Mutations (UniProt numbering) W24A, Q25K, Q26K, R27T, K28S
Insertions 494insHHHH
Deletions L2-V23
Sequence identity to UniProt 0.9894
auth_asym_id F
label_asym_ids of heme Q
Available structure PDB