Danish
Uniprot ID:  P22680
  • Protein: Cytochrome P450 7A1
  • Organism: Human (Homo sapiens)
  • Length: 504
  • Sequence:
    • MMTTSLIWGIAIAACCCLWLILGIRRRQTGEPPLENGLIPYLGCALQFGANPLEFLRANQRKHGHVFTCKLMGKYVHFITNPLSYHKVLCHGKYFDWKKFHFATSAKAFGHRSIDPMDGNTTENINDTFIKTLQGHALNSLTESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCYRVMFEAGYLTIFGRDLTRRDTQKAHILNNLDNFKQFDKVFPALVAGLPIHMFRTAHNAREKLAESLRHENLQKRESISELISLRMFLNDTLSTFDDLEKAKTHLVVLWASQANTIPATFWSLFQMIRNPEAMKAATEEVKRTLENAGQKVSLEGNPICLSQAELNDLPVLDSIIKESLRLSSASLNIRTAKEDFTLHLEDGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEIKQFLILMLSYFELELIEGQAKCPPLDQSRAGLGILPPLNDIEFKYKFKHL
Exclude chains with
Mutations (vs. UniProt)
Clear
Number of chains:  6
PDB ID:  pdb_00003v8d , Chain A 
Resolution 1.90 Å
Residue indices (Uniprot), coverage 24-505 (25-503), 0.97
Difference from Uniprot sequence engineered mutation:expression tag
Mutations (UniProt numbering) W19A, L20K, I21K, L22T, G23S, I24S, T104L, L504H
Insertions 502insHHHH
Deletions M2-L18
Sequence identity to UniProt 0.9836
auth_asym_id A
Missing residues 471GLU-473GLN
Structural gaps Exists
label_asym_ids of heme C
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.10 Å
PDB ID:  pdb_00003v8d , Chain B 
Resolution 1.90 Å
Residue indices (Uniprot), coverage 24-502 (25-503), 0.97
Difference from Uniprot sequence engineered mutation:expression tag
Mutations (UniProt numbering) W19A, L20K, I21K, L22T, G23S, I24S, T104L, L504H
Insertions 502insHHHH
Deletions M2-L18
Sequence identity to UniProt 0.9836
auth_asym_id B
Missing residues 158SER-163THR:329GLU-331ASN:471GLU-473GLN
Structural gaps Exists
label_asym_ids of heme M
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.12 Å
PDB ID:  pdb_00003dax , Chain A 
Resolution 2.15 Å
Residue indices (Uniprot), coverage 24-505 (25-503), 0.97
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) W19A, L20K, I21K, L22T, G23S, I24S, L504H
Insertions 502insHHHH
Deletions M2-L18
Sequence identity to UniProt 0.9856
auth_asym_id A
Missing residues 155PRO-164ALA
Structural gaps Exists
label_asym_ids of heme C
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.12 Å
PDB ID:  pdb_00003dax , Chain B 
Resolution 2.15 Å
Residue indices (Uniprot), coverage 24-502 (25-503), 0.97
Difference from Uniprot sequence expression tag
Mutations (UniProt numbering) W19A, L20K, I21K, L22T, G23S, I24S, L504H
Insertions 502insHHHH
Deletions M2-L18
Sequence identity to UniProt 0.9856
auth_asym_id B
Missing residues 155PRO-163THR
Structural gaps Exists
label_asym_ids of heme E
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.10 Å
PDB ID:  pdb_00003sn5 , Chain A 
Resolution 2.75 Å
Residue indices (Uniprot), coverage 24-503 (25-503), 0.97
Difference from Uniprot sequence engineered mutation:expression tag
Mutations (UniProt numbering) W19A, L20K, I21K, L22T, G23S, I24S, T104L, L504H
Insertions 502insHHHH
Deletions M2-L18
Sequence identity to UniProt 0.9836
auth_asym_id A
Missing residues 155PRO-162LYS:194ARG-197THR
Structural gaps Exists
label_asym_ids of heme C
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.12 Å
PDB ID:  pdb_00003sn5 , Chain B 
Resolution 2.75 Å
Residue indices (Uniprot), coverage 25-503 (25-503), 0.97
Difference from Uniprot sequence engineered mutation:expression tag
Mutations (UniProt numbering) W19A, L20K, I21K, L22T, G23S, I24S, T104L, L504H
Insertions 502insHHHH
Deletions M2-L18
Sequence identity to UniProt 0.9836
auth_asym_id B
Missing residues 155PRO-164ALA:471GLU-473GLN
Structural gaps Exists
label_asym_ids of heme I
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.16 Å