Uniprot ID: P22830
- Protein: Ferrochelatase, mitochondrial
- Organism: Human (Homo sapiens)
- Length: 423
- Sequence:
MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL
Number of chains: 14
| Resolution | 1.60 Å |
|---|---|
| Residue indices (Uniprot), coverage | 65-423 (65-423), 0.85 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | M1-K64 |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | None |
| Available structure | PDB |
| Resolution | 1.60 Å |
|---|---|
| Residue indices (Uniprot), coverage | 565-923 (65-423), 0.85 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | M1-K64 |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | B |
| label_asym_ids of heme | None |
| Available structure | PDB |
| Resolution | 1.80 Å |
|---|---|
| Residue indices (Uniprot), coverage | 65-423 (65-423), 0.85 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | M1-K64 |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | None |
| Available structure | PDB |
| Resolution | 1.80 Å |
|---|---|
| Residue indices (Uniprot), coverage | 565-923 (65-423), 0.85 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | M1-K64 |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | B |
| label_asym_ids of heme | None |
| Available structure | PDB |
| Resolution | 2.18 Å |
|---|---|
| Residue indices (Uniprot), coverage | 65-423 (65-423), 0.87 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| Mutations (UniProt numbering) | A56G, K57S, P58H, Q59H, V60H, Q61H, P62H, Q63H, K64G, E343Q |
| Insertions | None |
| Deletions | R2-Q54 |
| Sequence identity to UniProt | 0.9730 |
| auth_asym_id | A |
| label_asym_ids of heme | None |
| Available structure | PDB |
| Resolution | 2.18 Å |
|---|---|
| Residue indices (Uniprot), coverage | 65-423 (65-423), 0.87 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| Mutations (UniProt numbering) | A56G, K57S, P58H, Q59H, V60H, Q61H, P62H, Q63H, K64G, E343Q |
| Insertions | None |
| Deletions | R2-Q54 |
| Sequence identity to UniProt | 0.9730 |
| auth_asym_id | B |
| label_asym_ids of heme | None |
| Available structure | PDB |
| Resolution | 2.20 Å |
|---|---|
| Residue indices (Uniprot), coverage | 65-423 (65-423), 0.85 |
| Difference from Uniprot sequence | engineered mutation |
| Mutations (UniProt numbering) | F110A |
| Insertions | None |
| Deletions | M1-K64 |
| Sequence identity to UniProt | 0.9972 |
| auth_asym_id | A |
| label_asym_ids of heme | None |
| Available structure | PDB |
| Resolution | 2.20 Å |
|---|---|
| Residue indices (Uniprot), coverage | 65-423 (65-423), 0.85 |
| Difference from Uniprot sequence | engineered mutation |
| Mutations (UniProt numbering) | F110A |
| Insertions | None |
| Deletions | M1-K64 |
| Sequence identity to UniProt | 0.9972 |
| auth_asym_id | B |
| label_asym_ids of heme | None |
| Available structure | PDB |
| Resolution | 2.20 Å |
|---|---|
| Residue indices (Uniprot), coverage | 65-423 (65-423), 0.85 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | M1-K64 |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | A |
| label_asym_ids of heme | None |
| Available structure | PDB |
| Resolution | 2.20 Å |
|---|---|
| Residue indices (Uniprot), coverage | 565-923 (65-423), 0.85 |
| Mutations (UniProt numbering) | None |
| Insertions | None |
| Deletions | M1-K64 |
| Sequence identity to UniProt | 1.0000 |
| auth_asym_id | B |
| label_asym_ids of heme | H |
| Available structure | PDB |
| Resolution | 2.40 Å |
|---|---|
| Residue indices (Uniprot), coverage | 65-423 (65-423), 0.87 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| Mutations (UniProt numbering) | A56G, K57S, P58H, Q59H, V60H, Q61H, P62H, Q63H, K64G, F110A, E343D |
| Insertions | None |
| Deletions | R2-Q54 |
| Sequence identity to UniProt | 0.9703 |
| auth_asym_id | A |
| label_asym_ids of heme | D |
| Available structure | PDB |
| Resolution | 2.40 Å |
|---|---|
| Residue indices (Uniprot), coverage | 65-423 (65-423), 0.87 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| Mutations (UniProt numbering) | A56G, K57S, P58H, Q59H, V60H, Q61H, P62H, Q63H, K64G, F110A, E343D |
| Insertions | None |
| Deletions | R2-Q54 |
| Sequence identity to UniProt | 0.9703 |
| auth_asym_id | B |
| label_asym_ids of heme | G |
| Available structure | PDB |
| Resolution | 2.60 Å |
|---|---|
| Residue indices (Uniprot), coverage | 65-423 (65-423), 0.87 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| Mutations (UniProt numbering) | A56G, K57S, P58H, Q59H, V60H, Q61H, P62H, Q63H, K64G, M76H |
| Insertions | None |
| Deletions | R2-Q54 |
| Sequence identity to UniProt | 0.9730 |
| auth_asym_id | A |
| label_asym_ids of heme | C |
| Available structure | PDB |
| Resolution | 2.60 Å |
|---|---|
| Residue indices (Uniprot), coverage | 65-423 (65-423), 0.87 |
| Difference from Uniprot sequence | engineered mutation:expression tag |
| Mutations (UniProt numbering) | A56G, K57S, P58H, Q59H, V60H, Q61H, P62H, Q63H, K64G, M76H |
| Insertions | None |
| Deletions | R2-Q54 |
| Sequence identity to UniProt | 0.9730 |
| auth_asym_id | B |
| label_asym_ids of heme | H |
| Available structure | PDB |
