Danish
Uniprot ID:  Q9UNU6
  • Protein: 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
  • Organism: Human (Homo sapiens)
  • Length: 501
  • Sequence:
    • MVLWGPVLGALLVVIAGYLCLPGMLRQRRPWEPPLDKGTVPWLGHAMAFRKNMFEFLKRMRTKHGDVFTVQLGGQYFTFVMDPLSFGSILKDTQRKLDFGQYAKKLVLKVFGYRSVQGDHEMIHSASTKHLRGDGLKDLNETMLDSLSFVMLTSKGWSLDASCWHEDSLFRFCYYILFTAGYLSLFGYTKDKEQDLLQAGELFMEFRKFDLLFPRFVYSLLWPREWLEVGRLQRLFHKMLSVSHSQEKEGISNWLGNMLQFLREQGVPSAMQDKFNFMMLWASQGNTGPTSFWALLYLLKHPEAIRAVREEATQVLGEARLETKQSFAFKLGALQHTPVLDSVVEETLRLRAAPTLLRLVHEDYTLKMSSGQEYLFRHGDILALFPYLSVHMDPDIHPEPTVFKYDRFLNPNGSRKVDFFKTGKKIHHYTMPWGSGVSICPGRFFALSEVKLFILLMVTHFDLELVDPDTPLPHVDPQRWGFGTMQPSHDVRFRYRLHPTE
Exclude chains with
Mutations (vs. UniProt)
Clear
Number of chains:  2
PDB ID:  pdb_00007lyx , Chain A 
Resolution 2.60 Å
Residue indices (Uniprot), coverage 26-498 (26-501), 0.96
Difference from Uniprot sequence expression tag:initiating methionine
Mutations (UniProt numbering) C20A, L21K, P22K, G23T, M24S, L25S
Insertions 501insHHHHHH
Deletions V2-L19
Sequence identity to UniProt 0.9876
auth_asym_id A
Missing residues 245SER-246GLN:315VAL-330LYS
Structural gaps Exists
label_asym_ids of heme B
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.14 Å
PDB ID:  pdb_00008eoh , Chain A 
Resolution 2.65 Å
Residue indices (Uniprot), coverage 26-498 (26-501), 0.96
Difference from Uniprot sequence expression tag:initiating methionine
Mutations (UniProt numbering) C20A, L21K, P22K, G23T, M24S, L25S
Insertions 501insHHHHHH
Deletions V2-L19
Sequence identity to UniProt 0.9876
auth_asym_id A
Missing residues 245SER-247GLU:315VAL-330LYS
Structural gaps Exists
label_asym_ids of heme B
Available structure PDB and Modeled
RMSD of experimental residues after energy minimization 0.14 Å