Danish

PDB ID: pdb_00008zou

Respirasome open state 2 in presence of metformin (SC-MetO2)
Experimental method: ELECTRON MICROSCOPY
Resolution: unavailable
Deposition date: 2024-05-29

Number of assemblies: 1

Assembly ID: 0 (author_and_software_defined_assembly)
Structural data	including_not_modeled
Oligomeric count	79
label_asym_ids of protein	79 chains (5 with heme) A, AA, AB, AC, B, BA, BB, C, CA, CB, D, DA, DB, E, EA, EB, F, FA, FB, G, GA, GB, H, HA, HB, I, IA, IB, J, JA, JB, K, KA, KB, L, LA, LB, M, MA, MB, N, NA, NB, O, OA, OB, P, PA, PB, Q, QA, QB, R, RA, RB, S, SA, SB, T, TA, TB, U, UA, UB, V, VA, VB, W, WA, WB, X, XA, XB, Y, YA, YB, Z, ZA, ZB
label_asym_ids of heme	CG DF LD MD TF UF WE XE
label_asym_ids of the others	show AD (PEE), AE (PC1), AF (PEE), AG (CDL), BC (CDL), BD (CDL), BE (PC1), BF (CDL), BG (PC1), CC (ZN), CD (PLX), CE (3PE), CF (CDL), DC (PC1), DD (CDL), DE (PLX), DG (PC1), EC (PEE), ED (CDL), EE (3PE), EF (CDL), EG (FES), FC (PEE), FD (PC1), FE (PEE), FF (PLX), FG (PEE), GC (PC1), GD (PC1), GE (PC1), GF (PEE), GG (PEE), HC (3PE), HD (PC1), HE (CDL), HF (FES), HG (CDL), IC (PC1), ID (PEE), IE (PLX), IF (PX2), IG (PC1), JC (PEE), JD (PLX), JE (PC1), JF (PEE), JG (CDL), KC (PEE), KD (3PE), KE (CDL), KF (PC1), KG (SF4), LC (CDL), LE (PC1), LF (PLX), LG (SF4), MC (PEE), ME (PEE), MF (PC1), MG (FES), NC (CDL), ND (CU), NE (CDL), NF (PC1), NG (MG), OC (NDP), OD (MG), OE (CDL), OF (CDL), OG (ZN), PC (ZMP), PD (PC1), PE (PEE), PF (PEE), PG (SF4), QC (ZMP), QD (CDL), QE (PC1), QF (3PE), QG (PLX), RC (ADP), RD (PC1), RE (PEE), RF (CDL), RG (SF4), SC (CDL), SD (PEE), SE (PC1), SF (PEE), SG (SF4), TC (CDL), TD (PC1), TE (CDL), TG (PEE), UC (PEE), UD (PLX), UE (PC1), UG (PC1), VC (CDL), VD (CU), VE (PC1), VF (3PE), VG (SF4), WC (PLX), WD (CU), WF (PC1), WG (FMN), XC (PEE), XD (PC1), XF (PEE), XG (FES), YC (PLX), YD (PEE), YE (PEE), YF (PC1), ZC (CDL), ZD (PEE), ZE (PEE), ZF (PC1)

Each chain information

Showing all 79 chains (5 with heme). Show only chains with heme

Chain A
auth_asym_id	4L
Residue indices (Uniprot)	1-98 (1-98)
Uniprot ID	P56632 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain AA
auth_asym_id	B3
Residue indices (Uniprot)	12-91 (12-91)
Uniprot ID	A0A4X1VD84 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain AB
auth_asym_id	QF
Residue indices (Uniprot)	25-91 (25-91)
Uniprot ID	A0A8D1JI21 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain AC
auth_asym_id	V3
Residue indices (Uniprot)	382-423 (69-110)
Uniprot ID	I3LRR4 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain B
auth_asym_id	5A
Residue indices (Uniprot)	50-151 (50-151)
Uniprot ID	F1SJ34 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain BA
auth_asym_id	B4
Residue indices (Uniprot)	2-129 (2-129)
Uniprot ID	A0A4X1T6M0 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain BB
auth_asym_id	QG
Residue indices (Uniprot)	11-111 (11-111)
Uniprot ID	A0A286ZPR8 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain C
auth_asym_id	5B
Residue indices (Uniprot)	33-127 (33-127)
Uniprot ID	Q5S3G4 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain CA
auth_asym_id	B5
Residue indices (Uniprot)	52-189 (52-189)
Uniprot ID	F1SGC6 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain CB
auth_asym_id	QH
Residue indices (Uniprot)	3-80 (2-82)
Uniprot ID	A0A8D0SHY6 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain D
auth_asym_id	6A
Residue indices (Uniprot)	23-97 (23-97)
Uniprot ID	A0A287AEB7 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain DA
auth_asym_id	B6
Residue indices (Uniprot)	62-187 (62-187)
Structural gaps	Exists
Uniprot ID	A0A480KM09 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain DB
auth_asym_id	QI
Residue indices (Uniprot)	2-63 (2-64)
Uniprot ID	Q2EN79 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain E
auth_asym_id	6B
Residue indices (Uniprot)	5-86 (5-86)
Uniprot ID	A0A4X1TG97 ￫UniprotKB
S-S bonds	40:54
label_asym_ids of heme	None
Available structure	PDB

Chain EA
auth_asym_id	B7
Residue indices (Uniprot)	1-125 (1-125)
Uniprot ID	F1SCH1 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain EB
auth_asym_id	QJ
Residue indices (Uniprot)	1-49 (1-52)
Uniprot ID	F1SDI2 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain F
auth_asym_id	6C
Residue indices (Uniprot)	6-75 (6-75)
Uniprot ID	A0A4X1TXH1 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain FA
auth_asym_id	B8
Residue indices (Uniprot)	31-186 (31-186)
Uniprot ID	F1RWL7 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain FB
auth_asym_id	QK
Residue indices (Uniprot)	1-78 (1-274)
Missing residues	36ALA-40SER
Structural gaps	Exists
Uniprot ID	A0A4X1TWD8 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB and Modeled
RMSD of experimental residues after energy minimization	0.11 Å

Chain G
auth_asym_id	7A
Residue indices (Uniprot)	22-78 (22-78)
Uniprot ID	Q8SPJ9 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain GA
auth_asym_id	B9
Residue indices (Uniprot)	44-221 (44-221)
Uniprot ID	K7GSE5 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain GB
auth_asym_id	Qa
Residue indices (Uniprot)	35-453 (35-453)
Uniprot ID	F1RPD2 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain H
auth_asym_id	7B
Residue indices (Uniprot)	30-79 (30-79)
Uniprot ID	A0A287BJ57 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain HA
auth_asym_id	BK
Residue indices (Uniprot)	2-175 (124-299)
Uniprot ID	A0A8D0R7A9 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain HB
auth_asym_id	Qb
Residue indices (Uniprot)	36-480 (35-480)
Missing residues	253LEU-264ALA
Structural gaps	Exists
Uniprot ID	A0A8D0PK14 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB and Modeled
RMSD of experimental residues after energy minimization	0.12 Å

Chain I
auth_asym_id	7C
Residue indices (Uniprot)	17-63 (17-63)
Uniprot ID	Q1W0Y2 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain IA
auth_asym_id	BL
Residue indices (Uniprot)	53-151 (53-154)
Uniprot ID	A0A8D1EYI7 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain IB heme
auth_asym_id	Qc
Residue indices (Uniprot)	1-379 (1-379)
Mutations (UniProt numbering)	G314S
Uniprot ID	P24964 ￫UniprotKB
label_asym_ids of heme	TF , UF
Available structure	PDB

Chain J
auth_asym_id	8B
Residue indices (Uniprot)	25-67 (25-67)
Uniprot ID	A1XQT4 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain JA heme
auth_asym_id	C1
Residue indices (Uniprot)	1-514 (1-514)
Uniprot ID	O79876 ￫UniprotKB
label_asym_ids of heme	LD , MD
Available structure	PDB

Chain JB heme
auth_asym_id	Qd
Residue indices (Uniprot)	87-325 (86-326)
Uniprot ID	A0A287AZF9 ￫UniprotKB
label_asym_ids of heme	CG
Available structure	PDB

Chain K
auth_asym_id	A1
Residue indices (Uniprot)	1-70 (1-70)
Uniprot ID	K7GR43 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain KA
auth_asym_id	C2
Residue indices (Uniprot)	1-228 (1-228)
Uniprot ID	P50667 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain KB
auth_asym_id	Qe
Residue indices (Uniprot)	79-274 (1-274)
Uniprot ID	A0A4X1TWD8 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain L
auth_asym_id	A2
Residue indices (Uniprot)	14-98 (14-98)
Uniprot ID	F1RGE3 ￫UniprotKB
S-S bonds	24:58
label_asym_ids of heme	None
Available structure	PDB

Chain LA
auth_asym_id	C3
Residue indices (Uniprot)	2-261 (1-261)
Uniprot ID	Q35916 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain LB
auth_asym_id	Qf
Residue indices (Uniprot)	28-91 (25-91)
Uniprot ID	A0A8D1JI21 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain M
auth_asym_id	A3
Residue indices (Uniprot)	87-169 (2-84)
Uniprot ID	A0A4X1VQ42 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain MA
auth_asym_id	C4
Residue indices (Uniprot)	31-168 (31-168)
Uniprot ID	A0A4X1T8J9 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain MB
auth_asym_id	Qg
Residue indices (Uniprot)	11-111 (11-111)
Uniprot ID	A0A286ZPR8 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain N
auth_asym_id	A5
Residue indices (Uniprot)	5-116 (5-116)
Uniprot ID	A0A287BAW0 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain NA
auth_asym_id	CA
Residue indices (Uniprot)	28-76 (28-76)
Uniprot ID	A1XQS6 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain NB
auth_asym_id	Qh
Residue indices (Uniprot)	2-80 (2-82)
Uniprot ID	A0A8D0SHY6 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain O
auth_asym_id	A6
Residue indices (Uniprot)	41-154 (41-154)
Uniprot ID	F1SJP6 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain OA
auth_asym_id	CB
Residue indices (Uniprot)	2-122 (2-122)
Uniprot ID	A0A480JRW3 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain OB
auth_asym_id	Qi
Residue indices (Uniprot)	3-62 (2-64)
Uniprot ID	Q2EN79 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain P
auth_asym_id	A7
Residue indices (Uniprot)	2-113 (2-113)
Missing residues	75VAL-89GLU
Structural gaps	Exists
Uniprot ID	A0A8W4F7N8 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB and Modeled
RMSD of experimental residues after energy minimization	0.14 Å

Chain PA
auth_asym_id	N1
Residue indices (Uniprot)	1-318 (1-318)
Missing residues	203GLY-212ASN
Structural gaps	Exists
Uniprot ID	O79874 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB and Modeled
RMSD of experimental residues after energy minimization	0.11 Å

Chain PB
auth_asym_id	Qj
Residue indices (Uniprot)	2-52 (1-52)
Uniprot ID	F1SDI2 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain Q
auth_asym_id	A8
Residue indices (Uniprot)	79-249 (79-249)
Uniprot ID	F1SLR1 ￫UniprotKB
S-S bonds	113:143,123:133,155:187,165:177
label_asym_ids of heme	None
Available structure	PDB

Chain QA
auth_asym_id	N2
Residue indices (Uniprot)	1-347 (1-347)
Uniprot ID	O79875 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain QB
auth_asym_id	S1
Residue indices (Uniprot)	30-718 (30-718)
Uniprot ID	A0A4X1V1H9 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain R
auth_asym_id	A9
Residue indices (Uniprot)	36-376 (31-371)
Missing residues	358THR-363THR
Structural gaps	Exists
Uniprot ID	F1SL07 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB and Modeled
RMSD of experimental residues after energy minimization	0.13 Å

Chain RA
auth_asym_id	N3
Residue indices (Uniprot)	1-114 (1-114)
Missing residues	34THR-50PRO
Structural gaps	Exists
Uniprot ID	O79880 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB and Modeled
RMSD of experimental residues after energy minimization	0.10 Å

Chain RB
auth_asym_id	S2
Residue indices (Uniprot)	40-469 (40-469)
Missing residues	80ASP-84SER:124ARG-124ARG
Structural gaps	Exists
Nonstandard amino acids	2MR
Uniprot ID	F1S1A8 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB and Modeled
RMSD of experimental residues after energy minimization	0.10 Å

Chain S
auth_asym_id	AB
Residue indices (Uniprot)	76-152 (1-156)
Uniprot ID	A0A287AAR5 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain SA
auth_asym_id	N4
Residue indices (Uniprot)	1-459 (1-459)
Mutations (UniProt numbering)	M361V, A428P
Uniprot ID	O79881 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain SB
auth_asym_id	S3
Residue indices (Uniprot)	43-250 (43-250)
Uniprot ID	A0A286ZNN4 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain T
auth_asym_id	AC
Residue indices (Uniprot)	70-156 (1-156)
Uniprot ID	A0A287AAR5 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain TA
auth_asym_id	N5
Residue indices (Uniprot)	1-603 (1-603)
Mutations (UniProt numbering)	I13T, V122L
Uniprot ID	Q9TDR1 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain TB
auth_asym_id	S4
Residue indices (Uniprot)	52-175 (52-175)
Uniprot ID	A0A4X1SN37 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain U
auth_asym_id	AK
Residue indices (Uniprot)	38-357 (38-357)
Uniprot ID	F1SIS9 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain UA
auth_asym_id	N6
Residue indices (Uniprot)	2-175 (2-175)
Missing residues	76THR-85SER
Structural gaps	Exists
Uniprot ID	O79882 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB and Modeled
RMSD of experimental residues after energy minimization	0.11 Å

Chain UB
auth_asym_id	S5
Residue indices (Uniprot)	2-106 (2-106)
Uniprot ID	F1SV23 ￫UniprotKB
S-S bonds	33:66,43:56
label_asym_ids of heme	None
Available structure	PDB

Chain V
auth_asym_id	AL
Residue indices (Uniprot)	2-141 (2-141)
Uniprot ID	I3LGM4 ￫UniprotKB
S-S bonds	18:75,95:115
label_asym_ids of heme	None
Available structure	PDB

Chain VA
auth_asym_id	QA
Residue indices (Uniprot)	35-453 (35-453)
Uniprot ID	F1RPD2 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain VB
auth_asym_id	S6
Residue indices (Uniprot)	28-123 (28-123)
Uniprot ID	F1S031 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain W
auth_asym_id	AM
Residue indices (Uniprot)	2-145 (2-145)
Uniprot ID	F1SQP4 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain WA
auth_asym_id	QB
Residue indices (Uniprot)	35-480 (35-480)
Uniprot ID	A0A8D0PK14 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain WB
auth_asym_id	S7
Residue indices (Uniprot)	41-196 (41-196)
Uniprot ID	A0A8D1TL60 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain X
auth_asym_id	AN
Residue indices (Uniprot)	3-144 (3-144)
Uniprot ID	A0A8D1NRT6 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain XA heme
auth_asym_id	QC
Residue indices (Uniprot)	1-379 (1-379)
Mutations (UniProt numbering)	G314S
Uniprot ID	P24964 ￫UniprotKB
label_asym_ids of heme	WE , XE
Available structure	PDB

Chain XB
auth_asym_id	S8
Residue indices (Uniprot)	37-212 (64-239)
Uniprot ID	A0A286ZUN9 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain Y
auth_asym_id	B1
Residue indices (Uniprot)	3-58 (3-58)
Uniprot ID	A0A8D2CGH8 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain YA heme
auth_asym_id	QD
Residue indices (Uniprot)	86-326 (86-326)
Uniprot ID	A0A287AZF9 ￫UniprotKB
label_asym_ids of heme	DF
Available structure	PDB

Chain YB
auth_asym_id	V1
Residue indices (Uniprot)	30-460 (30-460)
Uniprot ID	A0A4X1SZP7 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain Z
auth_asym_id	B2
Residue indices (Uniprot)	38-104 (52-118)
Uniprot ID	A0A5G2QW32 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain ZA
auth_asym_id	QE
Residue indices (Uniprot)	79-274 (1-274)
Uniprot ID	A0A4X1TWD8 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB

Chain ZB
auth_asym_id	V2
Residue indices (Uniprot)	33-249 (33-249)
Uniprot ID	A0A287BG40 ￫UniprotKB
label_asym_ids of heme	None
Available structure	PDB